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Tumor Suppression Articles & Analysis: Older

12 articles found

Exploring the Potential of miRNA Mimics in Therapeutic Applications

Exploring the Potential of miRNA Mimics in Therapeutic Applications

Many studies have demonstrated that miRNA mimics can suppress tumor growth and metastasis by restoring the expression of tumor-suppressor genes. ...

ByCreative Biogene


Harnessing the Potential of Marine Polysaccharides as Valuable Resources

Harnessing the Potential of Marine Polysaccharides as Valuable Resources

Fucoidan derivatives have been shown to inhibit tumor cell growth, induce apoptosis, and suppress tumor metastasis. Additionally, marine polysaccharides exhibit antioxidant, anti-inflammatory, anticoagulant, and immunomodulatory activities, making them highly valuable for drug discovery and development. l Drug Delivery System In drug delivery ...

ByAlfa Chemistry


CADM: A New Generation of Tumor Suppressor Genes

CADM: A New Generation of Tumor Suppressor Genes

About Tumor Suppressor Genes A tumor suppressor gene, also known as anti-onco gene, is an essential component of the body's defense against cancer. ...

ByBeta Lifescience


B7-H3: Broad Prospects of Emerging Tumor Immunotherapy Targets

B7-H3: Broad Prospects of Emerging Tumor Immunotherapy Targets

This indicates that immunomodulatory therapy for tumors has matured, and with further research, clinical efficacy has been confirmed. ...

ByBeta Lifescience


Ozette’s computationally-driven analysis aids advancement of cancer drug development - Case study

Ozette’s computationally-driven analysis aids advancement of cancer drug development - Case study

Summary Inflammation is a hallmark of the tumor microenvironment and an area of active investigation. To better understand how tumor inflammation differs from general inflammation, such as in gum disease, Drs. ...

ByOzette Technologies


Introduction and Detection Methods for Phytochemicals

Introduction and Detection Methods for Phytochemicals

Classification and Functions of Common Phytochemicals Flavonoids Ÿ Species: Quercetin, brassin, catechin, lignan, anthocyanin, resveratrol Ÿ Functions: Anti-inflammatory, antibacterial, antioxidant, cancer prevention (breast cancer, ovarian cancer), lowering blood lipids and cholesterol Carotenoids Ÿ Species: Carotene, lutein, zeaxanthin, cryptoxanthin, capsaicin, lycopene Ÿ Functions: ...

ByCreative Proteomics


Modified bacteria produce tetanus toxin, which is utilized to treat fatal pancreatic cancer   

Modified bacteria produce tetanus toxin, which is utilized to treat fatal pancreatic cancer  

One reason for this is that pancreatic cancer is a "cold tumor" that the immune system is unable to recognize and eliminate. ...

ByCreative Biolabs


Enzyme Therapy and Cancer

Enzyme Therapy and Cancer

Two groups of experiments were conducted at the Michael Rees Hospital in Chicago. The experimental group is 21 to 31 years old, and the control group is 69 to 100 years old. Researchers found that the salivary amylase of young people is more than 30 times that of older people. This is why young people can easily digest sugar, bread, noodles, pastries, and cooked food. But these foods accelerate ...

ByCreative Enzymes


Aelan Cell Technologies publishes new research identifying biomarkers that could serve as companion diagnostics for patients being treated with IL-2

Aelan Cell Technologies publishes new research identifying biomarkers that could serve as companion diagnostics for patients being treated with IL-2

However, in older populations, MSCs no longer work with the immune system and actually provide cancerous tumors with a blood supply that aids in the invasiveness and metastasis of the tumor. ...

ByAelan Cell Technologies


The enhancement of Th1 immunity and the suppression of tumour growth by low-dose γ-radiation

The enhancement of Th1 immunity and the suppression of tumour growth by low-dose γ-radiation

To address if the modulation of immunity balance by low dose radiation is involved in the enhancement of the anti-tumour function, we examined the effect of 0.5 Gy γ-irradiation on the Th1/Th2 immunity balance in Ehrlich Solid Tumour (EST)-bearing mice. Repeated 0.5 Gy γ-irradiation significantly delayed the growth of tumours. The cytotoxic activities of Natural Killer (NK) cells and Cytotoxic T ...

ByInderscience Publishers


Polo-like kinase 1 is essential for early embryonic development and tumor suppression

Polo-like kinase 1 is essential for early embryonic development and tumor suppression

Polo-like kinases (Plks) are serine/threonine kinases that are highly conserved in organisms from yeasts to humans. Previous reports have shown that Plk1 is critical for all stages of mitosis and may play a role in DNA replication during S phase. While much work has focused on Plk1, little is known about the physiological function of Plk1 in vivo. To address this question, we generated Plk1 ...

ByAmerican Society for Microbiology (ASM)


The novel mechanism of metastasis inhibition by low-dose whole-body irradiation with gamma-rays

The novel mechanism of metastasis inhibition by low-dose whole-body irradiation with gamma-rays

The influence of repeated 0.5 Gy whole-body gamma-ray irradiation on tumour metastasis was examined from the standpoint of tumour invasion in the B16 melanoma pulmonary metastasis model in mice. We confirmed that 0.5 Gy whole-body gamma-ray irradiation (four doses over two weeks) significantly suppressed colony formation in the lungs. In the lung tissue 24 h after irradiation, both the level of ...

ByInderscience Publishers

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