Type 2 Diabetes Articles & Analysis: Older
50 articles found
This function is particularly important in the context of metabolic disorders such as obesity and type 2 diabetes. Impaired endothelial function in muscle microvasculature can lead to reduced insulin sensitivity and glucose uptake, further exacerbating metabolic dysregulation. ...
Dermal fibroblasts and leukocytes are the main sources of MMP, especially MMP-2. Platelets are an important source of MMP-1, MMP-2, MMP-3 and MMP-14. They are present in most connective tissues. MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12, MMP-13, and MT1-MMP and MT3-MMP are expressed in various vascular tissues and cells. ...
Diabetes is a common clinical disease, and with the improvement of living standards, an increase in the number of obese people, and the intensification of aging populations, the incidence of diabetes is increasing year by year. Diabetes has various types and requires long-term treatment. Antidiabetic drugs are essential for ...
Abstract Background: Assessment of short-term glycemic control can facilitate monitoring of diabetes development in at-risk individuals and monitoring response to lifestyle modification or medication. We evaluated salivary protein glycosylation levels as a novel, noninvasive, short-term glycemic index in comparison to hemoglobin A1c (HbA1c), fructosamine, 1,5-anhydroglucitol ...
Assessment of C-peptide levels can identify individuals at risk for or with type 1 diabetes with residual β-cell function in whom β cell-sparing interventions can be evaluated, and can aid in distinguishing type 2 diabetes from Latent Autoimmune Diabetes in Adults and late-onset ...
Dysbiosis, an imbalance in gut microbial communities, has been linked to altered bile acid metabolism and, consequently, to diseases like non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes. A landmark study conducted in collaboration with Creative Proteomics investigated the bidirectional relationship between bile acids and the gut ...
Diabetes, specifically Type 1 and Type 2 Diabetes Mellitus, remains one of the most commonly encountered metabolic diseases worldwide. The complexity and diversity of these conditions necessitate the development of detailed medical models for a comprehensive understanding of the diseases. Over time, ...
From the perspective of disease type, in all 204 countries and regions, type 2 diabetes cases accounted for more than 80% of all diabetes cases, and in 183 countries and regions with more than 89.7%, the prevalence of type 2 diabetes accounted for 96%. ...
FGL2 and disease Studies have found that FGL2 is highly expressed in microvascular endothelial cells, causing microcirculatory disturbance, promoting myocardial and liver ischemia-reperfusion injury, arthritis, type 2 diabetic heart failure, and type 2 diabetic nephropathy; FGL2 is highly ...
Metformin is a classic first-line hypoglycemic agent for patients with type 2 diabetes, and is an essential drug in combination regimenes. However, as the evidence is updated, the idea of drug selection for first-line treatment is changing. ...
In addition, our previous study also found that tetrahydrocurcumin has a good therapeutic effect on metabolic syndrome, obesity type 2 diabetes, hypertension, insulin resistance syndrome and other related diseases, and has a wide range of application prospects. 1.Hypoglycemic Effect Murugan P et al. induced type ...
BioLingus will position these products in the “epidemic” markets of obesity and type II diabetes : More than 400 MM people suffer from diabetes today. The global type 2 diabetes market is expected to grow to $58.7 billion by 2025, with an annual growth rate of 6.5%, according to ...
The global human insulin market is projected to surpass USD 40 Billion USD. Our sublingual “insulin+” product will be positioned in a particular segment of this market : it will be prescribed for type II diabetes patients, who do not respond sufficiently to GLP-1 analogues alone. Such a fixed dose combination is already on the market under the brand name Xultophy, which is a ...
The aim of this project is to develop low dose IL-2 for treatment of early onset juvenile Type I diabetes. Low dose injectable IL-2 in animal models has been shown to restore the balance between regulatory and effector T cells and, in this way, can help to reverse autoimmunity and the development of type I ...
Liraglutide and exenatide are both belonging to the class of diabetes products called GLP-1 analogues. The GLP-1 analogues have established themselves in the past years as one of the superior drug classes for treatment of diabetes type II in terms of blood glucose lowering and weight loss. Because of the latter, they are being used more and more also in the treatment of obesity. Until now, both ...
HFpEF is a complex disease which accounts for more than half of all heart failure (HF) hospital admissions and is an increasing disease burden. [1] The prevalence of HFpEF is climbing, reflecting an increasingly elderly and comorbid population, as well as reinforcing the need for more effective therapies.[2] SGLT2is are a class of anti-diabetic drugs that have ...
AdvaitaBio’s IPathwayGuide plays significant role in the research of a Stanford investigator. Stanford University is one of the world’s leading research and teaching institutions. With a 1.69 billion dollar annual sponsored research budget, Stanford has been delivering breakthrough discoveries in numerous domains. For over 6 years, Dr. Linda Yip has been conducting research at ...
He initially thought it was an allergic reaction to a new deodorant, but it wasn’t itchy, and it persisted after stopping the deodorant. The patient had a history of type 2 diabetes. On examination, a broad, well-demarcated, thin, scaly plaque was seen extending from the lateral chest over the axilla to the upper arm. ...
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Med., 2018, one may not need to test themselves several times a day if it is stable type 2 diabetes and on agents (drugs) that do not cause hypoglycemia. ...
Patient History Patient is a 40-year-old female with a history of type 2 diabetes. Patient presented to the Emergency Room with a diabetic foot ulcer and infection. ...