vaccine based Articles
-
Beyond Just Peptide Antigens: The complex world of peptide-based cancer vaccines
Therapeutic vaccines may well be the next wave of immunotherapy for cancer treatment. Peptide-based vaccines will play a pivotal role in the field. How is a peptide vaccine designed? What other factors such as adjuvants etc should be considered? Can Immunol oncological agents be synergetic with peptide vaccines? Read the full article: Beyond Just Peptide Antigens: The complex world of ...
-
Safety and immunogenicity of bivalent inactivated vaccine against haemorrhagic fever with renal syndrome in a phase II trial on healthy Chinese volunteers
We have developed a cell culture-derived, inactivated bivalent vaccine against both Haemorrhagic Fever with Renal Syndrome (HFRS) viruses 84 Fli (type I) and L99 (type II). This purified vaccine was tested in the clinical phase I/II trial in healthy non-infected adults in China. About 518 volunteers in Southern region and 650 volunteers from the Northern region of China were vaccinated. ...
-
Preventive cancer vaccine based on neoantigens gets put to the test
Studying the vaccine in dogs could provide insight into its effectiveness in people What if someone told you that a vaccine shot could prevent you from getting multiple types of cancer—ones as different from each other as breast cancer and lymphoma? Stephen A. Johnston, cofounder of the health-care start-up Calviri and a scientist at Arizona State University’s Biodesign Institute, ...
By Calviri
-
HIV-1 subtype C vaccine: waiting in wings for the human trials
India has more than 5 million people infected with HIV-1 and this number is likely to increase in coming years. It is estimated that by the turn of this decade more than 10 million people would have been infected with this virus. More than 90% of these infections are due to subtype C. Therefore, it is imperative that a vaccine be developed based on local circulating subtype and tested for ...
-
AKCP Wireless Tunnel COVID-19 Vaccine Monitoring Solution
AKCP Wireless Tunnel Solution Deployed for COVID-19 Vaccine Delivery and Storage In response to the pandemic, the Pfizer COVID-19 vaccine has been approved for use throughout the world. As the vaccine is based on mRNA technology it requires refrigeration to temperatures as low as -80°C. This is a challenge for the cold chain logistics industry. Monitoring the COVID-19 vaccine during delivery ...
By AKCP
-
Self-amplifying RNA as a tool to tackle emerging flavivirus outbreaks: lessons learned from the COVID-19 pandemic
Background Outbreaks of multiple Flaviviruses have afflicted humankind for centuries due to their rapid spread predominantly by arthropod vectors. Global warming has caused epidemics to emerge in previously unaffected regions. The SARS-CoV-2 outbreak and subsequent race in vaccine development can provide strategies to the scientific community to avoid a flavivirus pandemic. The COVID-19 battle ...
-
New Findings about Capsular polysaccharide You May Want to Know
Streptococcus pneumoniae is the leading cause of pneumonia, sepsis and meningitis. Collectively, these infections are a leading cause of morbidity and mortality in older adults and young children. To fight these deadly infections, a pneumococcal vaccine is given to stimulate the production of antibodies against CPS. However, bacteria can manipulate their CPS structure to evade these antibodies. ...
By CD BioGlyco.
-
Vaccine Manufacturing – how will supply chain complexity effect a distributed vaccine manufacturing network?
As of October 2021, 6-7 billion doses of COVID-19 vaccines have been provided under emergency measures. The vaccines roll out has peaked at 45 million doses/day and has remained broadly stable (Our Word in Data & WHO), so we can assume that this is the current global manufacturing capacity. But with only 35% of the worlds’ population fully vaccinated, we must also assume, along with ...
-
Vaccine Freezers for Vaccine Storage and Handling
Vaccine Freezers are required for the safe storage of vaccines that must be kept at extremely low temperatures. Without sufficient storage, a vaccine is likely to form deviations, drastically impacting the vaccines efficiency. At Froilabo we work to support the medical and pharmaceutical industry with the equipment they require to ensure safe storage solutions. Vaccine storage has been in high ...
-
Editorial: Research, Development and Clinical Trials for Peptide-Based Vaccines
From the eradication of smallpox through to the global response to the COVID-19 pandemic, vaccines have been a cornerstone in the fight against infectious diseases in humans and livestock since the 18th century. Although vaccines against COVID-19 are unlikely to eradicate the disease in the way that the smallpox vaccine did, they have proved very effective in preventing death and hospitalisation, ...
-
Identification and analysis of epitope-based malarial vaccine targets using computational biology
Malaria is a vector-borne infectious disease caused by protozoan parasite of the genus Plasmodium. The malaria vaccine which has been studied is designed to induce immunity to the sporozoite and to kill sporozoite-infected liver cells. A combination of bioinformatics approach and computational tools are used to screen and select antigen sequences as potential T-cell epitopes of supertype human ...
-
Envelope-based HIV vaccine peptides as antigens in HIV-1 immunodiagnostics
Many HIV-1 envelope-based synthetic peptides behave as antigenic mimics of linear or conformational epitopes generated in vivo in infected subjects, meaning they can be used as immunogens for antibody induction in appropriate animal models or as antigens in Enzyme-Linked Immunosorbent Assay (ELISA). These peptides are linear or branched, single sequenced or multi-epitopic, mostly representative ...
-
Flu shots urged as Madison’s FluGen plays role in effort for universal vaccine
David Wahlberg, Wisconsin State Journal October 18, 2018 With flu season approaching, health officials say people should get flu shots by the end of October, yet acknowledge that the annual vaccine generally works less than 60 percent of the time. The Madison company FluGen is part of a renewed national effort to improve the odds by developing a universal flu vaccine, which would protect ...
By FluGen, Inc.
-
The novel suspension quail cell line CCX.E10 is an ideal cell substrate for NDV virus and vector production
Newcastle disease is a highly infectious viral disease of the avian species. The causative agent is Newcastle disease virus (NDV), which belongs to the family of Paramyxoviridae. Many commercial vaccines, both live and inactivated, are available on the market and protect from NDV infection and disease. In addition, viral vectors based on Newcastle disease virus have been previously ...
By Nuvonis
-
Peptide Vaccine Design
Vaccines are considered one of the most successful medical interventions in the past few centuries, aiming to harness the human immune system and generate lasting protection against specific diseases. Traditional vaccines rely on the use of inactivated pathogens to trigger an immune response. However, many of these formulations carry a high risk of causing allergies or autoimmune reactions. ...
-
Bespoke mRNA Synthesis Service: Pioneering customizable RNA solutions in the Sphere of Biotechnology
In the ever-evolving realm of biotechnology, the astonishing advancements in mRNA (messenger RNAs) synthesis are poised to revolutionize various aspects of biological research. This article delineates the eclectic vistas opened up by custom mRNA synthesis services that provide bespoke, high-quality solutions for researchers globally. mRNA synthesis, an integral element of our genetic machinery, ...
-
Rational`s Experimental Herpes Vaccine Shows Preclinical Promise
Rational Vaccines said findings from a pilot study showed that RVX201 led to a reduction in recurrent genital lesions when compared to gD2-alum/MPL vaccine in animal studies. Rational's Experimental Herpes Vaccine Shows Preclinical Promise Rational Vaccines said findings from a pilot study showed that RVX201 led to a reduction in recurrent genital lesions when compared to gD2-alum/MPL vaccine ...
-
Unveiling the Potential of Premade RNA-LNP Products
Introduction RNA Lipid Nanoparticles (LNP) technology has rapidly gained prominence in the health and scientific domain, primarily due to its significant role in carrying the mRNA of the COVID-19 vaccines developed by Pfizer/BioNTech and Moderna. Yet, the potential of this technology spans beyond the confines of these vaccines or even the health industry. As research into premade RNA-LNP products ...
-
Micron developing microneedle technology for self-administration of vaccines and therapeutics
Closely-held Micron Biomedical is developing a dissolvable microneedle-based technology that could enable self-administration of vaccines and therapeutics. “While microneedle technology is not new, our company represents the evolution of the technology over many years,” Steven Damon, CEO, says in an interview with BioTuesdays.com. “We’re developing an innovative ...
-
Research And Development of Infectious Disease Vaccines
As of January 1, 2023, global vaccine development includes a total of 966 vaccine candidates, of which 23% (220) are traditional inactivated or attenuated vaccines. Advances in molecular technology have facilitated the development of other platforms, such as recombinant protein vaccines, nucleic acid vaccines, and viral vector vaccines, which have further diversified global vaccine development. ...
Need help finding the right suppliers? Try XPRT Sourcing. Let the XPRTs do the work for you