vaccine developed Articles
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Research And Development of Infectious Disease Vaccines
As of January 1, 2023, global vaccine development includes a total of 966 vaccine candidates, of which 23% (220) are traditional inactivated or attenuated vaccines. Advances in molecular technology have facilitated the development of other platforms, such as recombinant protein vaccines, nucleic acid vaccines, and viral vector vaccines, which have further diversified global vaccine development. ...
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Breaking Barriers: Harnessing the Potential of Adjuvants in Vaccine Development
Infectious diseases seriously threaten human health, and various infectious diseases may cause millions of severe cases and even death every year. Vaccination has been one of the most effective public health interventions in history, preventing millions of deaths worldwide. However, the success of vaccines relies not only on the antigens they carry but also on additional components known as ...
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Temperature Monitoring Supports the Vaccine Cold Chain
Vaccines play a vital role in society by preventing and eradicating various diseases. Newly developed vaccines such as pneumococcal conjugate vaccine (PCV) and rotavirus vaccines have the ability to save a million lives per year. The response to the 2019/2020 global COVID-19 pandemic resulted in mRNA ultra-low temperature vaccines being developed. It is essential for the efficacy of the vaccines ...
By AKCP
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Coronavirus: continued updates in basic research, vaccine development and testing
Researchers have delved further into our understanding of coronavirus, while the race to develop a vaccine continues. New advances in coronavirus understanding New research has put paid to some of the conspiracy theories surrounding coronavirus. A team comprising researchers from both the US, Australia and the UK has analyzed the receptor-binding domain (RBD) and the cleavage site present on ...
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Creative Enzymes Launches Advanced Neuraminidase for Flu Vaccine Development
Creative Enzymes, a professional enzyme provider located in New York, always hammers at researches and trials in order to provide customers with various enzymes as many as possible. Last week, the product manager of Creative Enzymes announced the launch of neuraminidase, which is expected to further develop a new universal influenza vaccine. Neuraminidase is a drug target to prevent the spread ...
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Duration of protection from live attenuated vs. sub unit HSV-2 vaccines in the guinea pig model of genital herpes: Reassessing efficacy using endpoints from clinical trials
Abstract Background Although herpes simplex viruses (HSV) are a major target for vaccine development no vaccine is currently licensed. Methods A live attenuated HSV virus vaccine, VC2 was compared to a subunit HSV vaccine, glycoprotein D (gD2) administered with the adjuvant, MPL/Alum using the guinea pig model of genital herpes. Three doses of intramuscular (IM) vaccine were provided followed by ...
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Developing Plasmodium falciparum malaria vaccines for populations living in areas with stable parasite transmission
Individuals living in areas with stable transmission of Plasmodium falciparum parasites develop substantial protective immunity to the disease during childhood. Because of naturally acquired immunity, which appears mainly to target parasite-encoded Variable Surface Antigens (VSA) on the Infected Erythrocytes (IE), severe and life-threatening disease among adults in such areas is rare. However, ...
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Robotic Liquid Handling Systems and the Future of Life Sciences
The pressure on clinical laboratories has increased significantly in recent years and the need for fast, accurate and thorough data is reaching unprecedented levels. COVID-19 has put an intense spotlight on automated liquid handling systems in particular, and with worldwide reliance and investment in PCR testing capabilities, this insatiable demand for rapid testing is unlikely to dissipate soon. ...
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The nanovaccine technology with huge potentials
Vaccines are an unparalleled medical milestone that has saved countless lives by harnessing the human immune system, according to the history of human development. Vaccine remains the most effective source of defense against the COVID-19 pandemic since 2020. The success of the lipid nanoparticle COVID-19 mRNA vaccine shows that nanotechnology can be used in vaccine development. Compared to ...
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Self-amplifying RNA as a tool to tackle emerging flavivirus outbreaks: lessons learned from the COVID-19 pandemic
Background Outbreaks of multiple Flaviviruses have afflicted humankind for centuries due to their rapid spread predominantly by arthropod vectors. Global warming has caused epidemics to emerge in previously unaffected regions. The SARS-CoV-2 outbreak and subsequent race in vaccine development can provide strategies to the scientific community to avoid a flavivirus pandemic. The COVID-19 battle ...
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Vaccine Projects
Abera’s vaccine delivery platform works as a plug-and-play system where known or novel antigens can be engineered onto our delivery platform to create effective, multivalent vaccines that are cost-effective and fast to produce. We actively work together with academia and industry to enable the use of our vaccine delivery platform in design and development of new vaccines. Many of these ...
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Possible role of molecular mimicry in pathogenesis of Ebola virus: implications for a rational vaccine design
Ebola Virus (EBOV) presents a challenge for vaccine development because immune correlates of protection in humans are not well known. In earlier studies we developed a concept of local similarity which refers to resemblance of structural patterns of unrelated proteins as a function of their amino acid composition. The search for local similarities between human and EBOV proteins was performed. ...
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The Importance of Vaccine Research and Quality Control
The controversy over vaccines and immunizations have become one of the most heavily debated topics. Vaccines have had the ability to save countless individuals from unnecessary illness, death, and have even helped to eliminate certain diseases. Over the last eight months, COVID-19 has created a global pandemic, to which there is currently no cure. As the virus continues to claim lives worldwide, ...
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Nature Biotechnology: Generation of a live attenuated influenza A vaccine by proteolysis targeting
Longlong Si's research group from the Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, published a research titled "Generation of a live attenuated influenza A vaccine by proteolysis targeting" in Nature Biotechnology. Using influenza virus as a model virus, the team established the technology of protein degradation targeting virus as an ...
By Profacgen
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Single-replication BM2SR vaccine provides sterilizing immunity and cross-lineage influenza B virus protection in mice
Abstract Both influenza A and B viruses cause outbreaks of seasonal influenza resulting in significant morbidity and mortality. There are two antigenically distinct lineages of influenza B virus, Yamagata lineage (YL) and Victoria lineage (VL). Since both B lineages have been co-circulating for years, more than 70% of influenza vaccines currently manufactured are quadrivalent consisting of ...
By FluGen, Inc.
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Bioprocess Automation, Remote Monitoring, and Real-Time Data Capture Underpin Operation Warp Speed’s Push for a COVID-19 Vaccine
Life science companies spanning the globe are striving to quickly develop and commercialize COVID-19 therapeutics and grab the brass ring of a viable, effective, and safe SARS-CoV-2 vaccine. In the United States, pharmaceutical and biotech companies, as well as Contract Development and Manufacturing Organizations (CDMOs), from coast-to-coast are racing to complete clinical trials and forge ...
By Lab Owl
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UW–Madison, FluGen, Bharat Biotech to develop CoroFlu, a coronavirus vaccine
MADISON, Wis.–(BUSINESS WIRE)–An international collaboration of virologists at the University of Wisconsin–Madison and the vaccine companies FluGen and Bharat Biotech has begun the development and testing of a unique vaccine against COVID-19 called CoroFlu. UW–Madison, FluGen, Bharat Biotech to develop CoroFlu, a coronavirus vaccineTweet this CoroFlu will build on the ...
By FluGen, Inc.
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HIV-1 subtype C vaccine: waiting in wings for the human trials
India has more than 5 million people infected with HIV-1 and this number is likely to increase in coming years. It is estimated that by the turn of this decade more than 10 million people would have been infected with this virus. More than 90% of these infections are due to subtype C. Therefore, it is imperative that a vaccine be developed based on local circulating subtype and tested for ...
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What are Vero cells?
Vero cellsare a continuous adherent cell line that is frequently used in cell culture and plays an important role in worldwide vaccine and vector production (manufacturing). Unlike other mammalian cells, they do not secrete interferon alpha or beta when infected by viruses – this is one of the reasons that efficient replication of many viruses can be achieved in Vero cells, ...
By Nuvonis
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How can Nuvonis help to fight the SARS-CoV-2 pandemics?
At the end of the year 2019, a cluster of severe pneumonia of unknown cause was described in Wuhan (Eastern China) and a SARS-like acute respiratory distress syndrome (ARDS) was noted in these patients. Early in January 2020, sequencing revealed a novel coronavirus (now termed SARS-CoV-2) as the causal factor for the disease designated as COVID-19. The pandemic caused by the virus has unforeseen ...
By Nuvonis
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