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Vaccine Trials Articles & Analysis

9 articles found

Rational Vaccines Announces a Clinical Trial to Determine Baseline Characteristics of Patients Diagnosed With Recurrent Symptomatic Herpes Simplex Type 2 (HSV-2) Virus

Rational Vaccines Announces a Clinical Trial to Determine Baseline Characteristics of Patients Diagnosed With Recurrent Symptomatic Herpes Simplex Type 2 (HSV-2) Virus

Results will inform protocol design of Phase 1/2 clinical trial of Company's lead HSV-2 therapeutic vaccine candidate WOBURN, Mass. and OXFORD, England, Aug. 15, 2022 /PRNewswire/ -- Rational Vaccines, a company focused on revolutionizing the treatment and prevention of herpes to eradicate the disease, today announced the launch of a clinical ...

ByRational Vaccines, Inc.


Preventive cancer vaccine based on neoantigens gets put to the test

Preventive cancer vaccine based on neoantigens gets put to the test

The study, called the Vaccination Against Canine Cancer Study, or VACCS, is the largest, most expensive interventional veterinary cancer trial to date. ...

ByCalviri


Medical Advancements

Medical Advancements

In the past few days, Moderna and Pfizer have released some promising clinical trials of their Covid-19 vaccinations. While these are still in the trial phase, many remain hopeful that the end of this deadly pandemic is near. ...

ByC&A Scientific


Will Covid-19 Vaccine Create a Dry Ice Shortage?

Will Covid-19 Vaccine Create a Dry Ice Shortage?

On November 9, 2020, Pfizer and BioNTech announced that their trial of a Covid-19 vaccine showed a 90% efficacy rate and very promising results in participants who had developed symptoms. ...

ByCoulson Ice Blast


UW–Madison, FluGen, Bharat Biotech to develop CoroFlu, a coronavirus vaccine

UW–Madison, FluGen, Bharat Biotech to develop CoroFlu, a coronavirus vaccine

CoroFlu could be in human clinical trials by the fall of 2020. Four Phase I and Phase II clinical trials involving hundreds of subjects have shown the M2SR flu vaccine to be safe and well tolerated. ...

ByFluGen, Inc.


A Bayesian design for phase I cancer therapeutic vaccine trials

A Bayesian design for phase I cancer therapeutic vaccine trials

However, these designs are poorly applicable for the development of cancer therapeutic vaccines because the expected safety concerns for these vaccines are not as much as cytotoxic agents. The primary objectives of a cancer therapeutic vaccine phase I trial thus often include determining whether the vaccine shows ...

ByOxford Vacmedix UK Limited


The Major Breakthrough That Completely Stopped This Woman`s Painful Genital Herpes Outbreaks

The Major Breakthrough That Completely Stopped This Woman`s Painful Genital Herpes Outbreaks

The clinical trial Mel participated in was the first live-attenuated herpes vaccine tested on humans. ...

ByRational Vaccines, Inc.


Preliminary evidence of efficacy from an open label trial of a therapeutic AIDS vaccine derived from the blood of HIV-positive donors

Preliminary evidence of efficacy from an open label trial of a therapeutic AIDS vaccine derived from the blood of HIV-positive donors

Two earlier reported studies indicated the beneficial clinical effects of THIVAC, a therapeutic HIV vaccine derived from the blood of HIV-positive donors. However, in those studies no stringent statistical analysis to support the beneficial clinical outcome was attempted. ...

ByInderscience Publishers


Safety and immunogenicity of bivalent inactivated vaccine against haemorrhagic fever with renal syndrome in a phase II trial on healthy Chinese volunteers

Safety and immunogenicity of bivalent inactivated vaccine against haemorrhagic fever with renal syndrome in a phase II trial on healthy Chinese volunteers

This purified vaccine was tested in the clinical phase I/II trial in healthy non-infected adults in China. About 518 volunteers in Southern region and 650 volunteers from the Northern region of China were vaccinated. Volunteers then received one or two boosts at two weeks post-vaccination. ...

ByInderscience Publishers

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