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Vascular Endothelial Growth Factor C Vegf C And Vegf D Is Not Equivalent To Vegf Articles & Analysis

10 articles found

Understanding Luminex Cytokine Panels and Their Role in Multiplex Cytokine Analysis   

Understanding Luminex Cytokine Panels and Their Role in Multiplex Cytokine Analysis  

Cytokines and growth factors are essential signaling molecules that play pivotal roles in immune regulation, inflammation, tissue repair, and numerous physiological and pathological processes. To comprehensively study these molecules, scientists often rely on high-throughput and sensitive technologies, among which Luminex Cytokine Panels have become a gold standard. This article delves into the ...

ByCreative Proteomics


Understanding Cytokines: Their Roles, Applications, and Detection   

Understanding Cytokines: Their Roles, Applications, and Detection  

Cytokines are a diverse group of small protein molecules that play crucial roles in the immune system and various biological processes. They are synthesized and secreted by a range of immune cells, including monocytes, macrophages, T cells, B cells, and natural killer (NK) cells, as well as certain non-immune cells like endothelial cells, epidermal cells, and fibroblasts. Cytokines are produced ...

ByCreative Proteomics


Cytokines: Characteristics, Applications, and Quantitative Analysis

Cytokines: Characteristics, Applications, and Quantitative Analysis

Cytokines represent a class of small protein molecules that exhibit diverse biological activities. These molecules are synthesized and secreted primarily by immune cells (including monocytes, macrophages, T cells, B cells, and NK cells) as well as certain non-immune cells (such as endothelial cells, epidermal cells, and fibroblasts) upon specific stimulation. Cytokines play pivotal roles in ...

ByCreative Proteomics


Huateng Pharma Supplies Minoxidil Intermediate 2,4-Diamino-6-chloropyrimidine (CAS NO.156-83-2)

Huateng Pharma Supplies Minoxidil Intermediate 2,4-Diamino-6-chloropyrimidine (CAS NO.156-83-2)

Minoxidil was first introduced by Upjohn Company of the United States, and was first used as an oral drug for the treatment of refractory hypertension in the 1970s. In later clinical applications, doctors observed hair regrowth and generalized excessive hair in balding patients, which led to the development of minoxidil preparations. Minoxidil can increase local blood supply, stimulate the ...

ByHunan Huateng Pharmaceutical Co. Ltd.


The Tumor Marker: Vascular Endothelial Growth Factor 165 (VEGF165)

The Tumor Marker: Vascular Endothelial Growth Factor 165 (VEGF165)

Tumors and Blood Vessel Growth Tumor, as an abnormal mass of cells, has blood vessels of various sizes that can be seen everywhere on the surface and deep within it. Nutrients for life are continuously supplied to the depths of tumor cells through these blood vessels. As the tumor continues to grow, nearby blood vessels also undergo rapid and chaotic growth, with these newly formed capillaries ...

ByBeta Lifescience


A Combination of Ramucirumab Plus Pembrolizumab Lengthened Survival For Some Lung Cancer Patients

A Combination of Ramucirumab Plus Pembrolizumab Lengthened Survival For Some Lung Cancer Patients

A study conducted under the Lung Cancer Master Protocol (Lung-MAP) found that when treated with a combination of ramuzumab (Cyramza) and Keytruda, Patients with advanced NSCLC whose cancer progressed during prior immunotherapy lived significantly longer than when treated with one of the current standard therapies for this cancer. The hazard ratio (80% confidence interval) for overall survival ...

ByHunan Huateng Pharmaceutical Co. Ltd.


Antibody-peptide epitope conjugate (APEC), another disguise for ADC   

Antibody-peptide epitope conjugate (APEC), another disguise for ADC  

Background Tumor immunotherapies compose immune checkpoint inhibitors, therapeutic antibodies, tumor vaccines, cellular therapies, and so on. However, each has its own set of issues, such as the fact that CAR-T therapy is an individual therapy that is costly; immune checkpoint inhibitors are highly effective, but only in some patients. The researchers expose us to a radically different way of ...

ByCreative Biolabs


What Are the Cytokines?

What Are the Cytokines?

Cytokines are a class of small molecule proteins secreted by cells that mediate and regulate immune processes, and they act in an autocrine, paracrine and endocrine manner. More than 200 types of human cytokines have been identified, which can be generally classified into interleukins, interferons, tumor necrosis factors, colony-stimulating factors, chemokines, growth factors, etc. according to ...

ByCreative Proteomics


Deletion of vascular endothelial growth factor c (vegf-c) and vegf-d is not equivalent to vegf receptor 3 deletion in mouse embryos

Deletion of vascular endothelial growth factor c (vegf-c) and vegf-d is not equivalent to vegf receptor 3 deletion in mouse embryos

Lymphatic vessels play an important role in the regulation of tissue fluid balance, immune responses, and fat adsorption and are involved in diseases including lymphedema and tumor metastasis. Vascular endothelial growth factor (VEGF) receptor 3 (VEGFR-3) is necessary for development of the blood vasculature during early embryogenesis, but later, VEGFR-3 expression becomes restricted to the ...

ByAmerican Society for Microbiology (ASM)


Possible role of molecular mimicry in pathogenesis of Ebola virus: implications for a rational vaccine design

Possible role of molecular mimicry in pathogenesis of Ebola virus: implications for a rational vaccine design

Ebola Virus (EBOV) presents a challenge for vaccine development because immune correlates of protection in humans are not well known. In earlier studies we developed a concept of local similarity which refers to resemblance of structural patterns of unrelated proteins as a function of their amino acid composition. The search for local similarities between human and EBOV proteins was performed. ...

ByInderscience Publishers

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