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Medical Industry Articles & Analysis: This-Year
169 articles found
In the bustling city of the cell, proteins are the tireless workers. They build structures, carry messages, and catalyze the chemical reactions essential for life. But a protein's job isn't static. Its function, location, and even its lifespan are tightly controlled by a series of modifications. Among the most versatile and critical of these is Protein Ubiquitination, a process that acts like a ...
In the intricate world of cellular biology, proteins are the undisputed workhorses. They are assembled based on a genetic blueprint, but their story doesn't end there. After synthesis, proteins undergo a vast array of chemical modifications known as post-translational modifications (PTMs). These changes act as molecular switches, fine-tuning a protein's function, localization, and stability. ...
ELANE, or neutrophil elastase (NE), is a serine protease stored in the azurophilic granules of neutrophils and is encoded by the ELANE gene on chromosome 19. It plays a pivotal role in the host defense system by degrading bacterial proteins, remodeling extracellular matrices, and shaping inflammatory responses. However, the same proteolytic activity that protects against pathogens can, when ...
Matrix Gla Protein (MGP) is a small, vitamin K-dependent extracellular matrix protein that plays a critical role in the regulation of vascular calcification and bone development. As a natural inhibitor of pathological mineralization, MGP has attracted significant attention in cardiovascular and skeletal biology research. The development of recombinant MGP protein has enabled researchers to study ...
When you hear the word "sterol," your mind probably jumps to one famous, and often misunderstood, molecule: cholesterol. We’re constantly bombarded with messages about "good" and "bad" cholesterol, and its impact on our cardiovascular health. But what if I told you that cholesterol is just one member of a vast and vital family of molecules called sterol lipids? This diverse group is ...
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Medical technology has seen remarkable advancements over the years, and radiopaque marker bands are among the innovations that have revolutionized the precision and safety of procedures involving medical devices. As a critical component in many medical instruments, these small yet highly effective devices ensure that surgeons and healthcare professionals perform accurately in high-stakes ...
Population growth, aging populations and increases in cancer incidence have necessitated new approaches to identifying effective treatments. One such approach involves the repositioning, or repurposing, of drugs already FDA approved in either non-oncology disease states and/or approved in a limited number of tumor types. The repurposing of these drugs for new indications represents an ...
A paper on the detection of phospholipids from skin via DMS has been published! The IonVision system was tested with porcine skin, and then further refined to analyze a small number of human basal cell carcinoma and healthy skin samples. The classification accuracies achieved (over 90 %!) encourage us to plan studies with a larger number of skin samples. The research article is available as ...
Virus-like particles (VLPs) have garnered significant attention in recent years for their potential applications in vaccine development, drug delivery, and as tools in various biotechnological fields. These nanoparticles mimic the structure of viruses but lack the viral genetic material that makes viruses infectious. This unique characteristic offers a versatile platform for various innovative ...
Induced pluripotent stem cells (iPSCs) have revolutionized the field of regenerative medicine and cellular biology. They are derived from somatic cells that have been genetically reprogrammed back into an embryonic-like pluripotent state. This transformation enables them to differentiate into any cell type, offering significant potential for disease modeling, drug discovery, and therapeutic ...
Human ovarian epithelial cells play a crucial role in ovarian function and have become a significant focus in cancer research, specifically ovarian cancer. The ability to study these cells in a laboratory setting has been greatly enhanced through the development of immortalized human ovarian epithelial cell lines, particularly those that utilize the SV40 (Simian Virus 40) large T antigen. ...
Immortalized human podocytes represent a significant advancement in the field of renal research, offering scientists an unprecedented opportunity to study kidney function and pathology. These specialized cells play a crucial role in the filtration barrier of the kidneys, and their immortality allows for extended experimentation beyond the limitations of primary cell cultures. Podocytes are unique ...
Abstract In pharmaceutical synthesis, heavy metal catalysts are commonly used, and their residues often remain in the final product. These heavy metals—primarily from catalyst residues—not only affect drug efficacy but also pose serious health risks to patients. As a result, pharmacopoeias in various countries impose strict limits on heavy metal content in pharmaceutical substances. ...
Advancements in medical technology have transformed healthcare, with radiopaque marker bands playing a crucial role in modern medical devices. These small components enhance precision and visibility during medical procedures and have become a key part of catheter designs, improving accuracy and efficiency. Edgetech Industries, a leading radiopaque marker bands manufacturer, provides high-quality ...
Introduction: Nitinol tubing has revolutionized the medical device industry, offering unparalleled flexibility and strength. Its unique properties, such as superelasticity and shape memory, have made it a preferred material for life-saving devices. This article explores the role of Nitinol Tube and Niti Hypotube in modern healthcare. The Role of Nitinol Tubing in Medical Devices: Nitinol tubing ...
A recent study led by Decan Jiang and colleagues from RWTH Aachen and Heidelberg University Hospitals in Germany has shed light on how porcine models are helping surgical training—particularly in the complex field of kidney transplantation. Pigs are anatomically and physiologically close to humans, making them ideal candidates for surgical training. Practicing renal ...
Post-transcriptional modifications of RNA molecules include methylation, acetylation deamination, isomerization, glycosylation, thiolation and pseudouracil modification among other types. Methylation represents the predominant post-transcriptional modification found within transfer RNA (tRNA) molecules. tRNA methylation has maintained its evolutionary conservation while also exhibiting dynamic ...
Oxygen monitoring during anesthesia remains fundamental to patient safety regardless of how medical standards have evolved over time. The American Society of Anesthesiologists (ASA) Standards for Basic Anesthetic Monitoring states that oxygen analyzers shall be positioned in the breathing circuit to monitor the concentration delivered to patients.1 The oxygen analyzer serves as one of the most ...
Whether you're out for a morning jog, hitting the beach, or driving into the sunset, you shouldn’t have to choose between clear vision and sun protection. That’s where women's prescription sunglasses come in — offering the perfect blend of fashion, function, and freedom.These aren’t just an accessory — they’re an everyday essential for women who want to see clearly without sacrificing style. Why ...