PCLS: An ex-vivo Window Into Lung Disease and Drug Discovery

Precision-Cut Lung Slices (PCLS) have emerged as a innovative ex vivo model that allows researchers to explore deep into lung physiology, disease mechanisms, and pharmacological responses. By offering a unique combination of biological complexity and controlled experimental conditions, PCLS serve as a critical bridge between the limitations of traditional in vitro cell cultures and the complexities of in vivo models. The versatility and precision of this technique have positioned PCLS as an invaluable tool in advancing our understanding of lung diseases and accelerating the discovery of novel treatments.