Plethysmography for the assessment of opioid-induced respiratory depression

Opioid-related addiction, overdose and death is a widespread public health crisis. A recent paper published in The Journal of Pharmacology and Experimental Therapeutics by Dr. Renata Marchette working within the National Institute on Drug Abuse Intramural Research Program provides a model example of the how plethysmography can be used to assess ventilatory behavior changes that occur with opioid administration.