The putative α-1,2-mannosyltransferase AfMnt1 of the opportunistic fungal pathogen aspergillus fumigatus is required for cell wall stability and full virulence
Proteins entering the eukaryotic secretory pathway commonly
are glycosylated. Important steps in this posttranslational modification are
carried out by mannosyltransferases. In this study, we investigated the
putative {alpha}-1,2-mannosyltransferase AfMnt1 of the human pathogenic mold
Aspergillus fumigatus. AfMnt1 belongs to a family of enzymes that comprises
nine members in Saccharomyces cerevisiae but only three in A. fumigatus. A
{Delta}afmnt1 mutant is viable and grows normally at
-
Most popular related searches
Customer comments
No comments were found for The putative α-1,2-mannosyltransferase AfMnt1 of the opportunistic fungal pathogen aspergillus fumigatus is required for cell wall stability and full virulence. Be the first to comment!