Site Specific and Global Epigenomic Editing

Site Specific and Global Epigenomic Editing: Principles and Applications, Volume 33 highlights the expanding role that epigenetics plays in pathogenesis, the full range of sites for possible epigenetic modification, and the potential to target these sites to modulate disease progression. The book answers key questions, including which of the hundreds of epigenomic marks and features are relevant, and which are likely to serve a role in regulating gene expression, cell behavior and phenotypic outcomes. This volume is the first to provide a thorough, conceptual introduction to epigenetic regulation and a thorough accounting of sites for possible epigenetic edits and disease modulation.