Addictions Management Articles
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CSX-1004: A Promising Canidate in the Fight Against the Fentanyl Crisis
The opioid crisis in the United States is a devastating public health issue, with over 70,000 overdose deaths annually, largely driven by the highly potent synthetic opioid fentanyl. The urgency to address this crisis has spurred the development of innovative therapies to prevent and reverse fentanyl overdoses. In this blog, we will explore the groundbreaking preclinical work on CSX-1004, a fully ...
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Plethysmography for the assessment of opioid-induced respiratory depression
Opioid-related addiction, overdose and death is a widespread public health crisis. A recent paper published in The Journal of Pharmacology and Experimental Therapeutics by Dr. Renata Marchette working within the National Institute on Drug Abuse Intramural Research Program provides a model example of the how plethysmography can be used to assess ventilatory behavior changes that occur with opioid ...
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Cytochrome P450: A Vital Biosynthetic Enzymes for Drug Metabolism
Overview of Cytochrome P450 Cytochrome P450 (CYP450), is a family of hemoglobin-coupled monooxygenases. In mammals, CYP450 oxidizes steroids, fatty acids, and xenobiotics, playing an important role in the metabolism of various compounds as well as in the synthesis and breakdown of hormones. In plants, they regulate the synthesis of defense compounds, fatty acids, and hormones. With the progress ...
By BOC Sciences
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CanaQuest Medical Corp (OTC: CANQF)
About: CanaQuest Medical is an award-winning, Clinical Stage/Life-Sciences company focused on the drug discovery and development of next-generation targeted therapeutics within the endocannabinoid system and specific brain receptors. The Company is focused on treating neurological conditions, such as epilepsy, anxiety, depression, and Post Traumatic Stress Disorder “PTSD,” including ...
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Temple research finds that tweaking CBD may help it curb pain and opioid use in mice
Doylestown-based Neuropathix is running safety tests required to start clinical trials in humans. The compound may help with neuropathy, a severe type of chronic pain associated with cancer treatment. The next generation of cannabis-inspired medicine might be grown in test tubes instead of greenhouses. Researchers at Temple University have partnered with Doylestown-based pharmaceutical company ...
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How Medical Studies are Changing the World
The coronavirus pandemic remains one of the top concerns within the United States. However, Johns Hopkins, and other research centers, are actively working to continue medical research in all divisions of medicine and health. Learn the ongoing studies at Johns Hopkins, what issues they are solving and how we can all make a difference. ...
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Combatting the Opioid Crisis with Cell Therapies for Chronic Back Pain
It’s no secret that opioid addiction is at an all-time high and represents a major public health threat. The CDC estimates that opioid addiction resulted in a record 72,000 drug overdose deaths in 2017 alone. What strikes me as one of the most tragic parts of this narrative is that so many of these deaths were people who became addicted to opioids after simply seeking relief ...
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Laser therapy offers pill-free foot pain relief
Sharon Whitt is settling in for a 10-minute treatment that she credits with getting the spring back in her step. “I like to dance, so that makes it a lot more comfortable to dance and not so much pain and pressure on the foot area,” she explains. Whitt was diagnosed with Morton’s Neuroma four years ago. It is a painful condition affecting nerves on the ball of the foot. ...
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