Clinical Medicine Articles

What to know of when searching for the best family chiropractor!

It is likely to see many people nowadays suffering from various kinds of physical health issues. These problems may be due to a number of reasons such as sports injuries, old age or else. Regardless of what health issue one may be experiencing, it is important to seek the needed help in order to recovery easily. Many people in today’s world therefore seek the aid of a professional ...

Aug. 26, 2021

By Safe Training Systems Ltd. (STS)

Detailed Introduction to Common Enzymes Used in Gene Cloning

The basic technology of genetic engineering is artificial cutting, splicing, and combination of genes. A gene is a DNA molecule with a certain function. To accurately cut out the DNA linear molecular fragments of different genes, various restriction endonucleases are required. To connect different fragments together, DNA ligase is required. To synthesize a gene or one of its fragments, DNA ...

Sep. 16, 2021

By Creative Enzymes

The Naming and Characteristics of Restriction Endonucleases

Restriction enzymes, also known as restriction endonucleases, are enzymes that can cut double-stranded DNA. Its cutting method is to cut the bond between the carbohydrate molecule and the phosphoric acid, and then create a nick on each of the two DNA strands without damaging the nucleotides and bases. There are two types of cleavage, which can produce sticky ends with protruding single-stranded ...

Sep. 12, 2021

By Creative Enzymes

Overview of Nitinol Material

Titanium nickel alloy, also known as Nitinol, is a binary alloy composed of nickel and titanium. The atomic percentages of these two elements are approximately equal. Austenitic phase and martensite phase Due to changes in temperature and mechanical pressure, Nitinol has two different crystal structure phases, namely an austenite phase and a martensite phase. In Nitinol, austenite is called the ...

Sep. 10, 2021

By Edgetech Industries LLC

An Overview of the Lipase and Its Industrial Applications

Lipase, also known as glyceride hydrolase, is a glycoprotein composed of 2%-15% sugar bases, the basic unit of which is mannose. Lipase exists in fat-containing animal, plant and microbial (such as mold, bacteria, etc.) tissues, including phosphatase, sterolase and carboxylesterase, fatty acids are widely used in food, medicine, leather, daily chemicals, etc. The Role of Lipase Lipase is an ...

Sep. 7, 2021

By Creative Enzymes

Gene of the Week: IL-6 (Exercise Recovery)

There are around 30,000 genes in the human genome. In this weekly series, we’ll write about a new gene featured in Orig3n DNA tests, so you can discover the kinds of information genetic assessments can offer you. Have you ever wondered how much recovery time your body needs following an intense workout? There’s a gene for that™! At Orig3n, we’re excited that professional ...

Aug. 31, 2021

By Orig3n

Gene of the Week: NQO1 (Skin Renewal)

There are around 30,000 genes in the human genome. In this weekly series, we’ll write about a new gene featured in Orig3n DNA tests, so you can discover the kinds of information genetic assessments can offer you. Have you ever wondered how or why your skin appears to be more or less youthful with the passing years? There’s a gene for that™! Spring is on the way, and you know ...

Aug. 31, 2021

By Orig3n

Global ADC Drug Overview

In recent years, antibody-drug conjugates (ADCs) have been widely sought after due to their excellent clinical performance and market returns. ADC drugs are composed of three parts: antibody, effector molecule (Payload, usually cytotoxic agent) and linker. Compared with traditional drugs, ADC drugs have obvious advantages in improving targeting and reducing side effects. 1. Global ADC listing ...

Aug. 28, 2021

By BOC Sciences

mRNA Delivery System

RNA is a hydrophilic, negatively charged macromolecule, and its ability to autonomously transmembrane is limited. Therefore, how to efficiently deliver mRNA to the cytoplasm and play a corresponding role is one of the key issues that limit the application of RNA therapy. The wide range of applications of therapeutic mRNA requires efficient and safe delivery methods. An ideal delivery system ...

Aug. 27, 2021

By BOC Sciences

The Reality and Future of Peptide Drugs

It has been said that the 21st century is the century of peptide drugs, and the fate of this substance, which lies between a large protein and a small molecule compound, is bound to be extraordinary. What are peptide drugs? Peptides are a class of compounds made up of amino acids linked by peptide bonds and are chemically active substances commonly found in living organisms. According to the ...

Aug. 24, 2021

By Creative Peptides

Antiseptic efficacy of an innovative perioperative surgical skin preparation: A confirmatory FDA phase 3 analysis - Case Study

Abstract Background: An innovative approach to perioperative antiseptic skin preparation is warranted because of potential adverse skin irritation, rare risk of serious allergic reaction, and perceived diminished clinical efficacy of current perioperative antiseptic agents. The results of a confirmatory US Food and Drug Administration (FDA) phase 3 efficacy analysis of a recently approved ...

Aug. 23, 2021

By Zurex Pharma

Efficacy and safety of a novel antimicrobial preoperative skin preparation - Case Study

Abstract Objective: Alternatives to skin preparation with conventional preoperative antiseptics are required because of adverse reactions and the potential emergence of resistance. Here, we present 2 phase 2 studies of ZuraGard (ZG), a novel formulation of isopropyl alcohol and functional excipients developed for preoperative skin antisepsis. Methods: Microbial skin flora on abdominal and ...

Aug. 23, 2021

By Zurex Pharma

Research and Development of Plant Extract Products

Extracts are liquid or solid natural active ingredients extracted from animal or plant raw materials. Plant extract is a product made from plants. It is formed by physicochemical extraction and separation process according to the needs of the use of the extracted final product, and directed acquisition and concentration of one or more active ingredients in the plant without changing the structure ...

Aug. 20, 2021

By Creative Enzymes

Detailed Introduction to the Four Effects of Probiotics

Probiotics, in simple terms, are a group of microorganisms that can effectively promote human health. They can resist gastric acid and bile acid, and can attach and colonize in the intestinal tract. According to statistics, the human gastrointestinal tract contains a rich and diverse microbial community, gathering more than 100 trillion microorganisms. These microbiomes encode more than 3 million ...

Aug. 19, 2021

By Creative Enzymes

Comparison of Enzyme Activity Assay Methods

Enzyme activity assay is an analytical technique that uses the properties of enzymes to specifically and efficiently catalyze chemical reactions, and detects the content and activity of certain enzymes in biological samples such as body fluids by measuring the rate of enzymatic reactions. 1. Classification by reaction time: Before the 1950s, the fixed-time method was mostly used. This method is ...

Aug. 16, 2021

By Creative Enzymes

Why Supplementing Digestive Enzymes Is Necessary for Most People?

Enzymes are proteins with catalytic functions in organisms. The distinguishing feature of enzymes is that they have a high degree of catalytic function and specificity, and the activity of enzymes can be adjusted, which is closely related to the conversion of different energy forms. Up to now, there are nearly 2,000 known enzymes. Digestive enzyme is one of them. It is mainly secreted by the ...

Aug. 11, 2021

By Creative Enzymes

Introduction to Anthocyanins

Anthocyanin Definition Anthocyanins, flavones, isoflavones, flavonols, and proanthocyanidins are all flavonoids that belong to a large group of important secondary metabolites widely found in plants. Anthocyanins are found in 72 genera of flowering plants (angiosperms) in 27 families. Among them, grapes, hawthorn, pine needles, and purple sweet potatoes have high anthocyanin content. The basic ...

Aug. 11, 2021

By Creative Proteomics

An Infection Prevention Wound Dressing - Case Study

Using Covalon’s patent-pending dual antimicrobial silicone adhesive technology, silver and chlorhexidine are combined right in the clear silicone adhesive film technology, providing superior comfort and protection throughout the entire surface area of the dressing. This dual antimicrobial combination boasts broad spectrum antimicrobial activity for at least 7 days and meets the current FDA ...

Aug. 10, 2021

By Covalon Technologies Ltd

The Development History and Applications of Enzyme Engineering

Enzyme engineering is a scientific technology that puts enzymes or microbial cells, animal and plant cells, organelles, etc. in a certain biological reaction device, and then use the biocatalytic function of the enzyme to transform the corresponding raw materials into useful substances and apply them to social life with the help of engineering means. It includes the preparation of enzyme ...

Aug. 10, 2021

By Creative Enzymes

Design and R&D of Covalent Drugs

For a long time, electrophilic groups have been a minefield in drug development. Therefore, in the classic medicinal chemistry textbooks of the past, it is always recommended to avoid introducing functional groups such as epoxide, acridine and Michael receptor into the structure of drug molecules, because these functional groups are highly reactive and may interact with a wide range of biological ...

Aug. 8, 2021

By BOC Sciences