Autoimmunity Applications
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Microscope System for Molecular imaging of cancer
Longitudinal imaging of pancreatic cancer. Monitor in a minimally invasive manner both tissue morphology and fibrosis (fluorescein) and cathepsin activity (Prosense® 680). A very thin probe (S 650) was used to monitor the pancreas of the same mouse over 9 months. ...
By Mauna Kea Technologies based in Paris, FRANCE.
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Klarity - Built Therapeutic Platform Technologies for Gastrointestinal Disease
A defective gastrointestinal (GI) barrier is associated with multiple conditions of high unmet need, including inflammatory bowel disease, chemotherapy-induced gut injury, food allergies, and celiac disease. We are advancing novel, oral, non-immunosuppressive therapeutics to improve GI barrier function. Our multi-targeted approach involves improving epithelial cell homeostasis, restoring appropriate immune responses, and repairing secretory cell ...
By Kallyope Inc. based in New York City, NEW YORK (USA).
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Peri-anal Fistula
Stempeucel® can reduce inflammation, which allows the tissues around the fistula tract to ...
By Stempeutics Research Pvt. Ltd. based in Bangalore, INDIA.
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Anti-CCP Assay for Rheumatoid Arthritis
Rheumatoid Arthritis (RA) is a common systemic autoimmune disease affecting between 0.5-1% of the adult population. RA is characterised by inflammation of the synovial joints which can lead to progressive joint destruction and consequently impair quality of life. ...
By Axis-Shield Diagnostics Ltd. based in Dundee, UNITED KINGDOM.
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IGX Platform Software for Autoimmunity
High-throughput analysis of immune repertoires has contributed to the elucidation of mechanistic underpinnings of autoimmunity, driving the development of novel therapies and better ...
By Enpicom B.V. based in s-Hertogenbosch, NETHERLANDS.
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Groundbreaking Proprietary Investigational Drug for Crohn`s disease
Effecting an estimated one million Americans, Crohn's disease can be highly debilitating and remains a serious burden for both patients and healthcare systems. ...
By RedHill Biopharma Ltd. based in Tel-Aviv, ISRAEL.
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Medical diagnostics solutions for inflammatory bowel disease sector
Inflammatory bowel disease (IBD), largely comprising the two conditions, Crohn’s Disease and Ulcerative Colitis, is now emerging as a global health problem. It now affects about 6 million people in Europe and US, comprising up to 620,000 in the UK (IBD Standards UK, 2013 Update). The symptoms of diarrhoea, abdominal pain and bloody stool substantially affect the quality of life of sufferers, and complications can be life threatening. IBD is also strongly associated with colorectal cancer development risk. ...
By DiagNodus Ltd. based in Cambridge, UNITED KINGDOM.
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IGX Platform Software for Immuno-Oncology
Monoclonal antibodies (mAbs) are used to treat patients in a variety of conditions such as infectious disease, cancer, and autoimmunity. Discovery of therapeutic antibodies is a laborious process, that depends on high-throughput screening of antibody candidates to determine antigen specificity. Immune repertoire analysis provides accurate, sensitive, and rapid detection of antibody sequences in panning rounds or exposured animal models, accelerating the discovery of ...
By Enpicom B.V. based in s-Hertogenbosch, NETHERLANDS.
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RNA Technology for Medical Areas of Focus Research
Using our platform, we are developing mRNA medicines for diverse uses and delivering them to patients across the globe. We are currently focusing on 4 medical areas - infectious diseases, immuno-oncology, rare diseases and autoimmune ...
By Moderna, Inc. based in Cambridge, MASSACHUSETTS (USA).
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Medical solutions for osteoporosis
Arthritis, a word that means painful joint, is an inflammatory process that affects the soft tissues of the joints of the human body; it is accompanied by swelling, redness, increased body temperature and pain. There are over one hundred types of arthritis, which can have several causes. The two main types of arthritis are: osteoarthritis, usually caused by normal wear and tear of the joint rheumatoid arthritis, one of the most common autoimmune diseases. Other types of arthritis can be caused by uric acid ...
By Neopharmed Gentili S.p.A. based in Milano, ITALY.
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PEMF
At Recover U we take a natural approach to well-being. PEMF (pulsed electromagnetic field) therapy is used to reactivate the body’s innate ability to heal itself. This healing modality has been used extensively in Europe for more than 70 years. Currently, in North America, PEMF is enjoying a true renaissance in the world of alternative and complementary medicine. There have been many talks on the method. Dr. Oz has extensively explained its benefits on his talk show. NASA has developed a device that uses ...
By Recover U Technologies and Services Inc. based in Toronto, ONTARIO (CANADA).
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Microbiome Therapeutics for Clinical Trials
Finch’s lead candidate, CP101, is in late-stage clinical development for the prevention of recurrent C. difficile infection (CDI), and has received Breakthrough Therapy and Fast Track designations from the U.S. Food and Drug Administration. In June 2020, Finch announced that CP101 met its primary efficacy endpoint in PRISM3, the first of two pivotal trials to support the development of CP101 for the prevention of recurrent CDI. PRISM4, a Phase 3 trial, is designed to serve as the second pivotal trial of ...
By Finch Therapeutics Group, Inc. based in Somerville, MASSACHUSETTS (USA).
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Proteome array screening solutions for protein array sector
The concept behind protein arrays is the immobilisation of sets of proteins, up to very large numbers, on solid supports, to perform miniaturised, multiplexed binding assays with a variety of potential ligands or interactants (see powerpoint presentation on right). HuProt v4 human proteome arrays as used at CPA comprise full length human proteins, many of which will retain their native conformation. HuProt arrays can be distinguished from arrays of peptides, used primarily to identify linear epitopes, or protein ...
By Cambridge Protein Arrays Ltd. (CPAP) based in Cambridge, UNITED KINGDOM.
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Proteome array screening solutions for autoantibody screening sector
Discover autoantigens in autoimmune diseases, delineate new candidate biomarkers. Autoantibodies are present in the blood of all healthy individuals. However, when directed at high levels against protein targets in specific tissues, autoantibodies can be a major cause of autoimmune diseases. They are also important biomarkers for diagnosis of these conditions. ...
By Cambridge Protein Arrays Ltd. (CPAP) based in Cambridge, UNITED KINGDOM.
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Probiotics: Pharmaceutical-Quality Innovative Solutions
The use of probiotics is a very promising alternative for the prevention and/or treatment of multiple health issues, in both humans and animals. By modifying the composition of the microbiota with probiotics, we may help to mitigate and solve upper respiratory, genitourinary or gastrointestinal tracts and periodontal infections, as well as dysbiosis issues related to fertility, premature births, dermatology, autoimmune diseases, and many more. The key is to choose the appropriate strain and dosage for each ...
By Zinereo Pharma based in Pontevedra, SPAIN.
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Portable Handheld Ultrasound Technology for Viral & Autoimmune Liver Disease Patients
Velacur can also be used to assess and manage other chronic liver diseases, resulting from viral infections, autoimmune disorders, metabolic diseases or excessive alcohol consumption. Like fatty liver disease, viral and autoimmune hepatitis are “silent” diseases of the liver. They show no symptoms until your liver is severely damaged, making it vital for early disease detection to limit progression and protect the health of your ...
By Sonic Incytes Medical Corp. based in Vancouver, BRITISH COLUMBIA (CANADA).
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