Coronavirus Articles
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Microbial Discovery - Case Study
Goal Understanding of Coronavirus (SARS-CoV-2) of interest using whole-genome sequence data from NCBI Solution Loci helps the scientists to understand the Coronavirus at the molecular level with a few click ...
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Influenza A virus replication has a stronger dependency on Raf/MEK/ERK signaling pathway activity than SARS-CoV-2
The recent COVID-19 pandemic again highlighted the urgent need for broad-spectrum antivirals, both for therapeutic use in acute viral infection and for pandemic preparedness in general. The targeting of host cell factors hijacked by viruses during their replication cycle presents one possible strategy for development of broad-spectrum antivirals. By inhibiting the Raf/MEK/ERK signaling pathway, ...
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Bespoke mRNA Synthesis Service: Pioneering customizable RNA solutions in the Sphere of Biotechnology
In the ever-evolving realm of biotechnology, the astonishing advancements in mRNA (messenger RNAs) synthesis are poised to revolutionize various aspects of biological research. This article delineates the eclectic vistas opened up by custom mRNA synthesis services that provide bespoke, high-quality solutions for researchers globally. mRNA synthesis, an integral element of our genetic machinery, ...
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Coronavirus Pandemic Likely Caused by Lab Leak
The coronavirus pandemic that could have been prevented After creating widespread global devastation and panic, the origin of the coronavirus pandemic has largely remained a mystery. Now, new information has emerged that reinforces a claim that it somehow began spreading in Wuhan, China. Citing a classified intelligence report provided to the White ...
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Norovirus is Spreading More Rapidly – and is on the rise
The very contagious illness, known as the stomach bug, is on the rise. The Centers for Disease Control and Prevention (CDC) has released data that confirms norovirus cases have seen a nationwide increase, outpacing last year’s numbers so far. The CDC reports that more than 15% of weekly tests for norovirus have come back positive, which is unusually ...
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How can Nuvonis help to fight the SARS-CoV-2 pandemics?
At the end of the year 2019, a cluster of severe pneumonia of unknown cause was described in Wuhan (Eastern China) and a SARS-like acute respiratory distress syndrome (ARDS) was noted in these patients. Early in January 2020, sequencing revealed a novel coronavirus (now termed SARS-CoV-2) as the causal factor for the disease designated as COVID-19. The pandemic caused by the virus has unforeseen ...
By Nuvonis
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What are Vero cells?
Vero cellsare a continuous adherent cell line that is frequently used in cell culture and plays an important role in worldwide vaccine and vector production (manufacturing). Unlike other mammalian cells, they do not secrete interferon alpha or beta when infected by viruses – this is one of the reasons that efficient replication of many viruses can be achieved in Vero cells, ...
By Nuvonis
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Project - Sublingual Interferon-alfa (BL SLIT II)
We plan to develop sublingual interferon-alfa for the prevention of viral infections, such as influenza and coronaviruses (such as COVID-19). The rise in prevalence of viral respiratory infections in humans and increase in health care expenditure are projected to boost the growth of the global respiratory antiviral treatment market. Respiratory syncytial virus, influenza virus, parainfluenza ...
By BioLingus AG
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Ozette’s AI in the battle against Covid - Case study
Summary The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic began in 2019 and rapidly scaled to a global presence of disease known as COVID-19. Despite the relatively fast implementation of testing and vaccination worldwide, the rise of emerging viral variants and breakthrough infections raises concerns that SARS-CoV-2 will continue to pose a global health threat. ...
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Teleradiology in Covid-19
The start of coronavirus pandemic pushed limits of healthcare systems all over the world by causing thousands of deaths and the requirement of a huge quantity of healthcare resources. When WHO declared COVID19 as a pandemic, the whole world came to standstill. Half of the world population is confined to their home except for essential services. In the year 2016, when GOI announced ...
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New structural target against COVID-19
A new structural target for drug development against COVID-19 has been unveiled today by Sibylla Biotech in collaboration with the Italian National Institute of Nuclear Physics (INFN), the University of Trento and University of Perugia.The breakthrough drug discovery strategy pioneered by Sibylla in this study would not only promise to reduce the risk of drug resistance and harmful side effects, ...
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Evaluation of the Talis One Covid-19 Test System for the Rapid Detection of Sars-Cov-2 and Emerging Variants
Introduction The discovery of a novel coronavirus in December 2019 in the Wuhan province of China and subsequent global spread has caused a pandemic of the scale not seen since the 1918 H1N1 pandemic. The novel coronavirus, classified as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is highly infectious and causes coronavirus disease 2019 (COVID-19), a respiratory and vascular ...
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When Respiratory Pathogen Metagenome Sequencing Meets Hybrid Capture Enrichment
Currently, the incidence of infectious diseases has increased globally, and the pathogens show a trend of diversification and complexity. Rapid and accurate pathogenic diagnosis, which enables early selection of sensitive anti-infective drugs or effective and targeted preventive and control measures, is the core of accurate prevention and treatment of infectious diseases. The epidemic of ...
By CD Genomics
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COVID-19 Disease Testing; Utilising Fluorescence During a Pandemic
While the world continues to endure loss and hardship due to the outbreak of COVID-19, caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), researchers are scrambling to provide test kits that are accurate, fast, sensitive, and widely available, especially as symptoms vary broadly and may not appear for days if at all. To this end, several diagnostic methods have been ...
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Spring is here - will the coronavirus die in summer?
Spring is fast approaching, and coronavirus restrictions are being lifted all over the northern hemisphere. Are we ready to loosen up protection? Is there hope the virus will die in summer? With time flying unnoticed, we are already into our third summer with coronavirus being part of our lives. As of today, almost 500 million people worldwide have been in contact with SARS-CoV-2. These, of ...
By Respiray OU
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Cytokine Storms and Viral Infections
Cytokines are small soluble proteins that are secreted by immune cells and tissue cells to play a regulatory role between cells, including interferon (IFN), interleukin (IL), chemokines, colony-stimulating factors (CSF), tumor necrosis factors (TNF) and so on. Cytokines function in autocrine, paracrine or endocrine forms, and can regulate cell growth and differentiation, modulate immune response ...
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Using AI to Fight a Pandemic: Insilico Medicine Announces Novel Preclinical Candidate for COVID-19 Treatment
Insilico Medicine announced the nomination of a novel preclinical therapeutic candidate for treating COVID-19, designed using the generative chemistry AI platform Chemistry42. The new drug candidate is a 3CL protease inhibitor unique from existing drugs in its class because it can be rapidly produced. While this nomination is a potentially important development for the ongoing COVID-19 pandemic ...
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COVID-19: It’s Not Over Yet
It’s hard to believe that it’s been more than 2 years since the World Health Organization (WHO) declared COVID-19 a global pandemic on March 11, 2020. At that time, the scientific world and public health communities all came together to identify the cause of this outbreak, to understand the type of “virus” infecting people and identify the infectious ...
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How Respiray can protect people with a weakened immune system
As countries worldwide start relaxing rules and lifting coronavirus restrictions, including wearing face masks in public, people with a weakened immune system may still need to protect themselves against airborne viruses and benefit from cleaner, purified air. ...
By Respiray OU
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How pregnant women can protect themselves from COVID-19, flu and other viruses
COVID-19 and viruses are a concern for all of us. Yet, anticipating a virus’s impact on an unborn child has heightened during the coronavirus pandemic for pregnant women or those expecting. However, there are tips you can take to protect yourself from viruses. ...
By Respiray OU
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