Gastrointestinal Tract Articles
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Hypoglycemic Functional Factors in Natural Products and Their Mechanisms of Action
Diabetes is a common clinical disease, and with the improvement of living standards, an increase in the number of obese people, and the intensification of aging populations, the incidence of diabetes is increasing year by year. Diabetes has various types and requires long-term treatment. Antidiabetic drugs are essential for people with the disease. These drugs can be classified into insulin ...
By BOC Sciences
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Four Novel Drug Delivery Systems You Should Know
In the field of medicine, effectively delivering drugs to the target site in the body is crucial for successful treatment. Over the years, several innovative drug delivery systems have been developed to improve drug efficacy and patient outcomes. In this article, we will discuss four novel drug delivery systems that have shown promising results in recent research. These systems include ...
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Development of mRNA-Directed Delivery - LNP Delivery System
During the COVID-19 pandemic, the success of mRNA vaccines has greatly propelled the development of mRNA therapeutics. mRNA is a negatively charged nucleic acid that serves as a template for protein synthesis in ribosomes. Despite its utility, the instability of mRNA necessitates appropriate carriers for in vivo delivery. Currently, lipid nanoparticles (LNPs) are the most mature approach for ...
By BOC Sciences
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Understanding Residual DNA Testing and Methods for Detecting Residual DNA
Most biological agents enter the body directly without passing through the gastrointestinal tract, so in addition to biological activity, relevant authorities have very strict requirements on impurities in drugs. Among them, the host cells residual DNA has always been the focus of regulatory agencies because of its special potential safety risks. Although recombinant protein drugs, antibody ...
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Understanding the Benefits of Probiotic Formula for Gut Health
The gut microbiota, a diverse community of microorganisms residing in our gastrointestinal tract, plays a crucial role in maintaining our overall health. Probiotics, live microorganisms with potential health benefits, have garnered significant attention for their ability to promote gut health. In this article, we will delve into the science behind probiotic formulas, exploring their mechanisms of ...
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How Probiotics Help Restore Balance to the Gut Microbiome
Probiotics are living microorganisms that offer numerous health benefits when consumed in adequate amounts. These beneficial bacteria can be found in various fermented foods such as yogurt, kefir, sauerkraut, and kimchi, as well as in dietary supplements. The term "probiotic" is derived from the Greek words "pro" and "biotic," which mean "for life." Probiotics have gained popularity in recent ...
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The Relationship Between Enzyme Function and Health
In the early 20th century, humans discovered vitamins, and then trace elements and minerals. It was only in the mid-1980s that humans realized the importance of enzymes. Nobel Prize in Physiology and Medicine Arthur Kornberg said: "For our lives, we can no longer find other substances as important as enzymes in nature." Enzymes control the entire body, and when enzymes function abnormally is ...
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SmartTab Completes Successful Preclinical Animal Studies for TargetTab™ Platform
SmartTab is pioneering a wireless remote controlled drug delivery system, has completed pre-clinical animal studies and is preparing for human clinical trials for its core technology TargetTab™. This proprietary and patented wireless capsule will revolutionize targeted drug delivery and medicine adherence. DENVER, CO — Prescription pills are often delivered to the wrong site, at ...
By SmartTab
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What is Total Parenteral Nutrition (TPN)
For patients and parents recently affected by or managing short bowel syndrome, TPN is likely new to their vocabulary. While any clinical acronym may sound overwhelming, TPN is not such a complicated one to understand. ...
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What Are the Health Benefits of Probiotics?
Probiotics are a type of beneficial bacteria that exist in the human gut itself. There are more than 100 trillion bacteria in the human gut, which are roughly divided into beneficial bacteria, intermediate bacteria and harmful bacteria. When the human body is healthy, the intestinal flora is in a balanced state, but when you have symptoms of constipation and diarrhea, it means that the number of ...
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What You Need to Know About Nutrition and Short Gut Syndrome
No parent wants to hear their child has a condition that might affect their education, family life, and overall well-being. Unfortunately, there’s currently no restorative treatment for short bowel syndrome (SBS). Monitoring nutrition is a lifelong necessity for anyone with this disorder. This means that no matter the cause of SBS, there are certain things you should know about nutrition ...
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Broad Application Areas of Cellulase Release Strong Market Demand
Cellulase (β-1,4-glucan-4-glucanohydrolase) is a general term for a group of enzymes that degrade cellulose to produce glucose. Cellulase is a kind of complex enzyme, including C1 enzyme, CX enzyme and glucosidase and other components. Among them, C1 enzyme and CX enzyme can decompose cellulose into cellobiose, and glucosidase can decompose cellobiose into glucose, thereby providing ...
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Mechanism of Action (MOA) of Disintegrant Excipients in Drug Formulation
Disintegration is an early way to evaluate whether a drug is effective. The disintegration time is an important control index for tablets, capsules, and dripping pills. Disintegration means that the solid preparation disintegrates and dissolves or breaks into granules under specified conditions. Except for insoluble coating materials or broken capsule shells, all solid preparations should pass ...
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Food Sources and Effects of Carotenoids
Carotenoid structure and category The major carotenoids contain α-carotene, β-carotene, γ-carotene, lutein, zeaxanthin, β-cryptoxanthin, lycopene, etc. Among the three isomers of carotenoids, β-carotene has the highest content and γ-carotene the least. α, β, γ-carotene and β-cryptoxanthin can be decomposed to form vitamin A, while lutein, ...
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An Overview of the Lipase and Its Industrial Applications
Lipase, also known as glyceride hydrolase, is a glycoprotein composed of 2%-15% sugar bases, the basic unit of which is mannose. Lipase exists in fat-containing animal, plant and microbial (such as mold, bacteria, etc.) tissues, including phosphatase, sterolase and carboxylesterase, fatty acids are widely used in food, medicine, leather, daily chemicals, etc. The Role of Lipase Lipase is an ...
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Detailed Introduction to the Four Effects of Probiotics
Probiotics, in simple terms, are a group of microorganisms that can effectively promote human health. They can resist gastric acid and bile acid, and can attach and colonize in the intestinal tract. According to statistics, the human gastrointestinal tract contains a rich and diverse microbial community, gathering more than 100 trillion microorganisms. These microbiomes encode more than 3 million ...
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Rani Therapeutics Debuts on the Nasdaq: What uou should know About the Biopharma
IMPORTANT MESSAGE: Benzinga prides itself as a media platform that is "For the People, By the People." We understand the markets are scary right now. For that reason, we are here to help. For today only get access to our #1 Options Newsletter for only $1. Rani Therapeutics Holdings, Inc. RANI+ Free Alerts, a San Jose, California-based early stage biopharma, debuted Friday on the Nasdaq ...
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8 Health Benefits of Taking Probiotics
Probiotics refer to a certain number of live microorganisms that can have a beneficial effect on the health of the host. At present, there are more than 20 kinds of probiotics used in China, mainly including Bifidobacterium, Lactobacillus, Clostridium butyricum, Saccharomyces boulardii, Enterococcus, Bacillus licheniformis and Bacillus cereus. Probiotics have eight major functions. 1. Maintain ...
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Detailed Introduction to Clinical Significance of Amylase
As a kind of enzymes for diagnostic use. Serum amylase (AMS) is the main type of amylase in serum. It belongs to glycoside chain hydrolase, which is mainly derived from the pancreas. In addition, there are also a small amount of secretion in the proximal duodenum, lung, uterus, and breast during lactation. Amylase plays an important role in the digestion of polysaccharide compounds in food. The ...
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Accurately Recapitulating Environmental Niches in Vitro Models of the Intestine
Advanced microphysiological systems can replicate aspects of intestinal complexity, such as epithelium self-renewal by stem cells in in vitro crypts or the interactions of microbes and intestinal epithelium mediated by a mucus layer. Availability of such models is key to progress in compound screening, disease modeling, and microbiome research. Defining a Niche A niche is a multidimensional ...
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