Human Physiology Articles
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Food Nutrition Enhancers
Food nutrition enhancer, also called food nutritional fortifier, refers to natural or synthetic nutrients added to food in order to increase its nutritional content. It can not only supplements people's daily nutritional intake, but also has a positive effect on disease prevention and control. The food nutrition enhancers can be divided into four main categories as following. Vitamins Vitamins ...
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NEBS and PIEZO2: Guardians of the Respiratory Galaxy
In a recent Nature publication by Schappe,M (2024), researchers have revealed a fascinating aspect of respiratory physiology: the role of sensory neurons in guarding against airway obstruction and orchestrating crucial reflexes to maintain respiratory function. The study explores the intricate neural pathways involved in detecting and responding to airway closure. By characterizing a ...
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An In-depth Analysis of hERG (IKr, Kv11.1): Its Function, Role, and Importance
Introduction hERG, which stands shorthand for the human Ether-à-go-go-Related Gene, generates the protein responsible for a certain type of potassium channel in the human heart, denoted as IKr or Kv11.1. The role of this potassium channel is fundamental for normal cardiac function, playing a vital role in the termination of the cardiac action potential and ultimately contributing to the ...
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The Science Behind Dietary Supplements: Exploring Efficacy and Safety of Popular Ingredients
Dietary supplements have become increasingly popular in recent years as individuals seek to optimize their health and well-being. When it comes to popular dietary supplement ingredients, several categories stand out, including vitamins, minerals, amino acids, enzymes, botanicals, and more. Each of these components plays a crucial role in supporting various physiological functions in the human ...
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Preclinical Animal Models as A Resource to Explore Rare Diseases
Rare diseases, also known as orphan diseases, are a diverse group of disorders that affect a small percentage of the population. Due to their low prevalence and limited understanding, treating and finding cures for these conditions present significant challenges. However, preclinical animal models have emerged as invaluable resources for advancing research and unraveling the mysteries surrounding ...
By Protheragen
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Wound Care Nurse Teaching:DOs and DON'Ts for Wounds Healing
Introduction Nursing the wounds is something we all need to think about, whether it's dealing with a little cut from a DIY project at home, a tumble outdoors, or a surgical procedure. And as the body get age, the skin wounds become more frequent. It's time to understand the advantage wound care for for optimal healing. This article offersexpert-approved advice to help you manage different types ...
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Overview of Microbial Epigenetics
Introduction to Microbial Epigenetics Epigenetics has been defined as the study of stable alterations in gene expression potentials that arise during development and cell proliferation, or alterations in DNA function without alterations in DNA sequence. Modern epigenetic features refer to the alteration of DNA and/or associated proteins without nucleotide sequence variance, which transmits the ...
By CD Genomics
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The Beginner's Guide to Exosome RNA-Seq
Exosomes are small extracellular vesicles that contain RNA, proteins, and lipids. These vesicles play a crucial role in intercellular communication and have been implicated in various physiological and pathological processes. Exosome RNA-Seq is a powerful technique that can be used to study the RNA content of exosomes and gain insight into their function and regulation. In this guide, we will ...
By CD Genomics
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Bile Acid: A Comprehensive Exploration of Function and Metabolism
In the realm of biological sciences, bile acids stand as pivotal molecules, playing a multifaceted role in various physiological processes within organisms. Bile acids are specialized molecules synthesized from cholesterol within the liver. These amphipathic compounds possess a hydrophilic region (carboxylic acid moiety) and a hydrophobic region (steroid backbone). Their distinctive structure ...
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A Closer Look at Metabolic Disease Models and Diabetes Models
Diabetes, specifically Type 1 and Type 2 Diabetes Mellitus, remains one of the most commonly encountered metabolic diseases worldwide. The complexity and diversity of these conditions necessitate the development of detailed medical models for a comprehensive understanding of the diseases. Over time, Type 1 and Type 2 Diabetes Mellitus Models, Metabolic Disease Models, and generalized Diabetes ...
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Harnessing the Potential of Marine Polysaccharides as Valuable Resources
Source of Marine Polysaccharides Marine polysaccharides are primarily sourced from a diverse range of marine organisms that thrive in oceans and seas. Seaweeds are the primary and most abundant source of marine polysaccharides. Seaweeds with high polysaccharide content, such as red algae (Rhodophyta), brown algae (Phaeophyceae), and green algae (Chlorophyta), have been extensively studied for ...
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AMPK Signaling Pathway and Function
AMPK (Adenosine 5'-monophosphate (AMP)-activated protein kinase), as an important kinase regulating energy homeostasis, is one of the central regulators of eukaryotic cell and organism metabolism. It is responsible for regulating cellular capacity input and output and maintaining the smooth functioning of cellular physiological activities. AMPK is also a key protein involved in various signaling ...
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Bespoke mRNA Synthesis Service: Pioneering customizable RNA solutions in the Sphere of Biotechnology
In the ever-evolving realm of biotechnology, the astonishing advancements in mRNA (messenger RNAs) synthesis are poised to revolutionize various aspects of biological research. This article delineates the eclectic vistas opened up by custom mRNA synthesis services that provide bespoke, high-quality solutions for researchers globally. mRNA synthesis, an integral element of our genetic machinery, ...
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Advanced Approaches in Inducible Expression Stable Cell Line Development
Harnessing the power of cell biology, scientists across the globe are perpetually invested in the pursuit of understanding the complexities of cellular mechanisms and their adaptability. One such venture is the creation of Inducible Expression Stable Cell Line (IESCL) development. IESCL signifies a consolidated methodology designed to explore the potentialities of modulated gene expression. This ...
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The Sophisticated Mechanism of Epigenetic Induction Facilitating Cellular Proliferation Service
The intricate nature of cellular growth and proliferation has been a fascinating subject of study for cell biologists for many decades. Recently, with the advent of cutting-edge gene manipulation and control techniques, increasing emphasis has been laid on comprehending the role of epigenetic induction in facilitating cell growth. This article focuses on shedding light on the ingenious process of ...
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Based on Antibody Targeted Protein Degradation
In recent years, PROteolysis TArgeting Chimeras (PROTAC), which utilizes the cell's own degradation mechanisms to eliminate specific disease-related proteins, has emerged as one of the most promising methods. Apart from PROTAC, various targeted protein degradation (TPD) strategies are emerging, involving molecular glue, Autophagy-Targeting Chimera (AUTEC), Autophagosome Tethering Compound ...
By BOC Sciences
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Advantages and Process of Chemical Crosslinking Mass Spectrometry
Chemical cross-linking mass spectrometry (CXMS) is an important tool for resolving protein structures and studying protein interactions. The technique uses a chemical cross-linking agent to link two amino acids in close enough spatial proximity to each other in a covalent bond. The two amino acid sites where cross-linking occurs are identified by mass spectrometry. The distance between the two ...
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Classes and Applications of Cell-Penetrating Peptides
Classes of Cell-Penetrating Peptides There are many types of cell-penetrating peptides (CPPs), and their classification is based on physicochemical properties, sources, intake mechanisms, and biomedical applications. There is no unified conclusion yet. According to their physical and chemical properties, CPPs can be divided into three types: cationic, amphiphilic and hydrophobic, among which ...
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What Is Microbiome and How to Study It
The term microbiome comes from the Greek word micro which means small and bios meaning life. It is defined as "a characteristic microbial community occupying a reasonable well-defined habitat which has distinct physiochemical properties". Many researchers in the past defined microbiome based on different contexts such as ecological and genetic aspects. However, scientists noted some gaps in these ...
By CD Genomics
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The Role of Chx10 Neurons in Global Motor Arrest
A recent study by Goni-Erro et al (2023) in Nature Neuroscience has shed light on a fascinating phenomenon: the neural control of global motor arrest. From the cessation of goal-directed actions to a broader motor arrest in response to fear or environmental cues, this complex behavior involves an intricate set of neuronal pathways. This recent study reveals that the activation of ...
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