Insulin Articles
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Hypoglycemic Functional Factors in Natural Products and Their Mechanisms of Action
Diabetes is a common clinical disease, and with the improvement of living standards, an increase in the number of obese people, and the intensification of aging populations, the incidence of diabetes is increasing year by year. Diabetes has various types and requires long-term treatment. Antidiabetic drugs are essential for people with the disease. These drugs can be classified into insulin ...
By BOC Sciences
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A Closer Look at Metabolic Disease Models and Diabetes Models
Diabetes, specifically Type 1 and Type 2 Diabetes Mellitus, remains one of the most commonly encountered metabolic diseases worldwide. The complexity and diversity of these conditions necessitate the development of detailed medical models for a comprehensive understanding of the diseases. Over time, Type 1 and Type 2 Diabetes Mellitus Models, Metabolic Disease Models, and generalized Diabetes ...
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Overview of Diabetes: Prevalence Assessment, Treatment And Prevention
Diabetes is a chronic disease that affects more than 540 million people worldwide and is one of the leading causes of death and disability worldwide. In China, there are more than 114 million adults with diabetes, accounting for about a quarter of the world's diabetes patients. With the change of living and eating habits, diabetes has become the third major factor affecting human health after ...
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History Development of Hydrogels
Hydrogels are composed of hydrophilic polymers, whose three-dimensional network structure can not only absorb a large amount of water, but also be used to carry drugs. Hydrogels prepared with suitable materials have the characteristics of high biocompatibility, mechanical and viscoelastic control. Since the term was coined in the late 19th century, hydrogels have been widely used in drug ...
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Project - Sublingual insulin+ (fixed dose combination product of insulin and exenatide/liraglutide)
The global human insulin market is projected to surpass USD 40 Billion USD. Our sublingual “insulin+” product will be positioned in a particular segment of this market : it will be prescribed for type II diabetes patients, who do not respond sufficiently to GLP-1 analogues alone. Such a fixed dose combination is already on the market under the brand name Xultophy, which is a ...
By BioLingus AG
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Health Mythbusting: Does eating turkey really make you tired?
This holiday season, Americans will consume around 87 million turkeys. And after they gobble down their turkey dinners, they might experience post-meal sleepiness. Often, people blame turkey as the cause. But does turkey actually make you tired? Why? What's in it? And what other factors are at play? In today’s article, we’ll break down the health myth of whether eating ...
By Evidation
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Diabetic Burnout: What is it & how can we help ourselves?
Diabetes is a chronic health condition that affects how your body turns food into energy. Most of the food you eat is broken down into sugar and released into your bloodstream. When your blood sugar goes up, it signals your pancreas to release insulin. Insulin acts like a key turning on cells with sugar as fuel (energy). Diabetes affects your body’s ability to produce or use that insulin. ...
By EO2 Concepts
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Beyond Insulin: Immunotherapy for Type 1 Diabetes-PI
Type 1 diabetes (T1D) is a complex T-cell-mediated autoimmune disease that results in the destruction of insulin-producing beta cells and inadequate insulin secretion. Prior to the discovery of insulin in 1921, patients with T1D died within a year or two of diagnosis. Since the discovery and mass production of insulin, T1D is no longer a terminal disease. However, over time, many patients still ...
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Diabetes: Medications, Treatments, and Remedies
Lifestyle can have a big impact on how your body handles blood glucose and sometimes a change in habits and activities is all that’s needed to prevent or better manage diabetes. But if changes in lifestyle aren’t enough to keep blood sugar levels normal, your doctor may prescribe medication to help lower insulin levels or insulin therapy. We’ll discuss here the most often ...
By Genteel LLC
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How to Know if your Blood Sugar is Low
If you go to a doctor regularly, and you should, more than likely you have had your blood tested for sugar levels. A high blood sugar or glucose level can be an indicator for the onset of prediabetes or diabetes. Too much sugar for anyone of any age can be dangerous. But what if you have low blood glucose levels or hypoglycemia? Whether you have diabetes or not low blood sugar levels can be ...
By Genteel LLC
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The Naming and Characteristics of Restriction Endonucleases
Restriction enzymes, also known as restriction endonucleases, are enzymes that can cut double-stranded DNA. Its cutting method is to cut the bond between the carbohydrate molecule and the phosphoric acid, and then create a nick on each of the two DNA strands without damaging the nucleotides and bases. There are two types of cleavage, which can produce sticky ends with protruding single-stranded ...
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How to support healthy blood sugar levels.
Healthy blood sugar levels are important for everyone. Maintaining healthy blood sugar levels can help reduce the risk of developing diabetes, kidney dysfunction, and problems with your eyes, gums, and nerves. Day-to-day healthy blood sugar levels will help with balancing energy levels, maintaining focus, and stabilizing mood. What Is “Blood Sugar?” Blood sugar, also known as ...
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Creating a Natural Microenvironment for Culturing Islet Cells
Type 1 diabetes is an autoimmune disease that leads to destruction of pancreatic islet cells. For many years, islet transplantation has been the focus of intense investigation as an insulin replacement therapy. Although transplantation immediately achieves insulin independence, the natural ability to continue producing insulin all but disappears 5 years later. There are many problems with ...
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Biorep Innovation Partner to COVID-19 Stem Cell Therapy Trial
After a lightning round of proposals and reviews, an international team of scientists led by Dr. Camillo Ricordi was granted immediate FDA authorization for a 24-patient clinical trial to test the safety and exploratory efficacy of umbilical cord-derived mesenchymal stem cells (UC-MSCs) to block the life-threatening lung inflammation that accompanies severe cases of COVID-19. The therapy uses ...
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Israeli artificial pancreas may one day cure diabetes
The Engineered Micro Pancreas from Betalin Therapeutics is heading closer to clinical trials in humans. Ahead of International Diabetes Day, November 14, Israeli startup Betalin Therapeutics announced that it is beginning the application process for clinical trials of its revolutionary artificial pancreas. Betalin’s Engineered Micro Pancreas (EMP) aims to free patients suffering from the ...
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Jerusalem firm in funding bid to test ‘micro-pancreas’ on humans
An implantable ‘micro-pancreas’ with the ability to produce insulin in response to blood glucose levels has been created by Israeli scientists. Betalin Therapeutics has tested the technology on animals with some success and is now looking to raise enough funds to be able to put it through clinical trials. It combines cells and a biological scaffolding, which situates those cells and ...
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The Reality of Diabetes Reversal
The conversation around diabetes reversal has increased, and when researching diabetes there are numerous states to this claim, but how realistic is it? Sadly, diabetes affects a huge number of people worldwide and is responsible for blindness, kidney disease, limb amputation and death. WHO estimates that diabetes was the seventh leading cause of death in 2016[1] and 422 million adults currently ...
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Efficient Wastewater cleaning for Insulin Production
Insulin production using biotechnology is now a standard procedure, but it leads to a high level of contaminated wastewater due to tensides which are difficult to break down. A solution provided by EnviroChemie shows how production wastewater output with varying levels of contamination and toxicity can be cleaned efficiently. It combines aerobic and anaerobic steps as well as a low-temperature ...
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How treatment of homes for termites decades ago may cause diabetes today
Obesity has been accepted as a risk factor for diabetes but results of four recently published studies have now revealed that insecticides in fat of patients may be the real risk factor. The initial investigations showed that the expected association between obesity and diabetes/insulin resistance was absent in people who had low levels of organochlorine insecticides in their blood (1, 2). ...
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Increased insulin action in skip heterozygous knockout mice
Insulin controls glucose homeostasis and lipid metabolism, and insulin impairment plays a critical role in the pathogenesis of diabetes mellitus. Human skeletal muscle and kidney enriched inositol polyphosphate phosphatase (SKIP) is a member of the phosphatidylinositol 3,4,5-trisphosphate phosphatase family (T. Ijuin et al. J. Biol. Chem. 275:10870-10875, 2000; T. Ijuin and T. Takenawa, Mol. ...
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