Advanced BioMatrix, Inc.
Advanced BioMatrix is a leader in the life science of three dimensional (3D) applications for tissue culture, cell assay, bioprinting and cell proliferation. Our products are recognized as the standard for purity, functionality and consistency. We have extensive expertise in production, isolation, purification, lyophilization, cell culture and testing of proteins, adhesion peptides, attachment factors, bioinks, substrate rigidity, and other 3D matrix products. Our expertise and knowledge are being employed to assure that our products are of the highest quality, consistent from lot-to-lot and easy-to-use for our research customers. See our expertise.
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- Globally (various continents)
This company also provides solutions for other industrial applications.
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The company is located in the San Diego region – one of the world’s largest life science and biotechnology clusters. Advanced BioMatrix has been manufacturing and delivering high quality products for research uses and applications for over 10 years. We continue to add several innovative new products each year that provide research tools for our customers worldwide. We develop new products and technologies within our company and also collaborate with many research institutes, universities and life science companies.
We are committed to our company vision of 'Transforming science to a new level of discovery by providing advanced technologies through innovative 3D matrix products.'
In 2021, Advanced BioMatrix was acquired by BICO.
Founded in 2016, BICO (formerly CELLINK) is the world’s leading bioconvergence company, organized into three business areas: Biosciences, Bioautomation, and Bioprinting. BICOaims to reduce the organ shortage and speed up drug development by providing accessible life science solutions that combine biology and technology, fundamentally shifting the global healthcare industry.
Using a combination of robotics, artificial intelligence, advanced genomics, and 3D bioprinting, our innovative technologies enable researchers and practitioners in the life sciences to conduct cell line development, perform high-throughput drug screening and diagnostics, and print human tissues and organs for the medical, pharmaceutical, and cosmetic industries. BICO is the future of life-saving treatments, as we enable our customers to improve people's health and lives.
We have over 32,000 installed instruments in more than 3,500 laboratories, including the top 20 pharmaceutical companies. They are being used in more than 65 countries, and have been cited in more than 11,000 publications. BICO is listed on Nasdaq Stockholm under BICO.
Advanced BioMatrix’s facilities are located in the San Diego region in Carlsbad, California, USA. Our state-of-the-art 7,300 sq. ft facility is designed for operational efficiency of materials, personnel and activities. Controls have been instituted to segregate operations where necessary to avoid mix-ups and possible contamination. Facility suites have been built for raw material preparation, clean room manufacturing, quality control, cell culture, bioprinting, R&D labs, fabrication of rigidity cultureware and cold chain distribution. Our order fulfillment, technical and customer service functions are closely housed to provide optimal service to our customers.
Why 3D Matters
The behavior of 3D-cultured cells is more reflective of in vivo cellular responses. 3D cell culture systems represent more accurately the actual microenvironment found in tissues in the body. Research has shown that cells in a 3D culture environment differ morphologically and physiologically from cells in a 2D culture environment.
The additional dimensionality of 3D culture is the crucial feature leading to the difference in cellular responses because not only does it influence the spatial organization of the cell surface receptors engaged in interactions with surrounding cells, but it also induces physical constraints to cells. These spatial and physical aspects in 3D cultures affect the signal transduction from the outside to the inside of the cells, and ultimately influence gene expression and cellular behavior. The adjacent diagram provides a depiction of the effects of 3D verse 2D of cell culture systems.
Advanced BioMatrix has a flexible and versatile mindset looking for opportunities to collaborate with many entities to bring new technologies and products to its customers.
We have worked closely with companies of all sizes, universities, research institutes, suppliers, customers and individuals to translate technology into products and tools that help researchers solve problems and make scientific break-throughs.