ALZET Osmotic Pumps products

ALZET Osmotic Pumps are small, implantable pumps for research in mice, rats, and other laboratory animals. These minipumps deliver drugs, hormones, and other test agents at continuous and controlled rates, for durations ranging from one day to six weeks, without the need for external connections or frequent handling. Their unattended operation eliminates the need for repeated nighttime or weekend dosing by lab personnel.

The AutoClip & Reflex wound closure systems provide a fast and effective alternative to sutures for closing wounds. They are the perfect solution for quickly closing incisions made for ALZET® pump implantations, enabling researchers to streamline surgeries and save valuable time. The 9 mm AutoClips are ideal for use in rats, while the 7 mm Reflex clips are optimum for mice and young rats. The automatic, spring-loaded applier is easy to use, and the clips provide maximum holding force with minimal animal trauma. When the incision is healed, the wound clips are easily removed using the remover. The components are available separate, or as a kit containing the Applier, Remover, and stainless steel wound clips (7 mm or 9 mm). All components are supplied non-sterile, but may be autoclaved.

The iPRECIO programmable pump is an advanced infusion device for drug delivery applications in mice, rats and larger animals. With versatile programmable functions and a refillable reservoir, this implantable infusion pump enables full control over dosing studies and empowers researchers to execute even the most complex dosing protocols, including multiple bolus dosing, variable/constant delivery, escalating drug administration, and more.

These stainless steel devices facilitate stereotaxic placement of brain cannula onto the skull of laboratory animals for CNS delivery applications. They are specially designed to grip the removable tab on all ALZET brain infusion cannulae during brain cannulation. These cannula holders are compatible with most of the common stereotaxic frames available (i.e., Stoelting, Kopf, WPI, MyNeuroLab and Harvard Apparatus).

Many agents do not cross the blood-brain barrier sufficiently to evaluate their effects on the brain without delivering them locally. Cerebral injection is one local delivery method, but it can be challenging to deliver an effective dose in a physiologically-compatible volume. In addition, the agent may not remain in the target location long enough to see an effect. For many compounds, local infusion directly into the brain is the only way to generate reliable data. ALZET pumps have been used in hundreds of published neuroscience studies to infuse agents, from growth factors to siRNA to psychoactive drugs and more, to the central nervous system.