8 products found
Amoy Diagnostics Co., Ltd. Products
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Real-time PCR Assays
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AmoyDx - Pan Lung Cancer PCR Panel
Lung cancer is one of the most common malignant tumor, and 80~85% of lung cancers are non-small cell lung cancer (NSCLC). There are many driver mutations in NSCLC. The frequency of mutations in NSCLC for EGFR, HER2, KRAS and BRAF genes are respectively 10-50%, 1-4%, 5-25% and 1-2%. About 3-7%, 1%, 1%, 0.12%, 0.02%, 0.08% ...
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AmoyDx - Model PIK3CA - Mutation Detection Kit
The phosphoinositide-3 -kinase catalytic alpha (PIK3CA) gene produces the p110 alpha (pl 10a) protein, which is one subunit of an enzyme called phosphatidylinositol 3-kinase (PI3K). PI3K plays a key role ofPI3K/Akt signaling pathway in numerous cellular processes critical for cancer progression, including metabolism, growth, survival, and motility. Somatic ...
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AmoyDx - Novel Coronavirus (2019-nCoV) Detection Kit
The novel coronaviruses belong to the p genus. COVID-19 is an acute respiratory infectious disease. People are generally susceptible. Currently, the patients infected by the novel coronavirus are the main source of infection; asymptomatic infected people can also be an infectious source. Based on the current epidemiological investigation, the incubation period is 1 to 14 days, mostly 3 to 7 days. The main manifestations include fever, fatigue and ...
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AmoyDx - Model NTRK - Gene Fusions Detection Kit
Neurotrophic tropomyosin-related kinase (NTRK) is a group of high affinity nerve growth factor (NGF) receptors, including tropomyosin receptor kinases (Trk) A, B, and C which are encoded by NTRK1, NTRK2, and NTRK3 genes, respectively. NTRK proteins, upon NGF ligand binding, function in the ...
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AmoyDx - Multi-Gene Mutations Detection Kit
Lung cancer is one of the most common malignant tumor, and 80~85% of lung cancers are non-small cell lung cancer (NSCLC). There are many driver mutations in NSCLC. The frequency of mutations in patients with NSCLC for the EGFR gene is 10~35%, for KRAS 15?25%, ...
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NGS Assays
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AmoyDx - HRD Focus Panel
The Homologous Recombination Repair (HRR) pathway plays an important role in the repair of double-strand breaks, which is a major cause of cancer development. It has been demonstrated that loss of function of HRR genes, Homologous Recombination Deficiency (HRD) is the inability to repair double strand breaks and will cause a higher risk of developing cancer[1-5]. Patients with HRD showed higher responses to poly ADP ribose ...
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AmoyDx - Model BRCA1 and BRCA2 - Gene Mutation Detection Kit
The AmoyDx BRCA1 and BRCA2 Gene Mutation Detection Kit (Reversible Terminator Sequencing) is intended for qualitative detection of BRCA1 and BRCA2 variants using DNA isolated from peripheral whole blood, fresh-frozen tissue or formalin-fixed paraffin-embedded (FFPE) tissue samples. The kit provides full and uniform coverage of both BRCA1 and BRCA2 genes, covering all coding exons, exon/intron junctions, some introns and UTR ...
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AmoyDx - Handle HRR NGS Panel
The Homologous Recombination Repair (HRR) pathway plays an important role in double strand break, which is the major cause of cancer development. It has been demonstrated that loss of function of HRR genes (e.g. BRCA1, BRCA2, PALB2) and homologous recombination deficiency (HRD) will cause a higher risk of developing cancer, and patients with HRR gene mutations showed higher response to PARPi and platinum-containing ...