Anatolia Geneworks products

It is well known that the accuracy of the thermal cycles and achieving temperature uniformity between tubes, so that all samples undergo the same thermal conditions, are prerequisite for a reliable PCR reaction. Key to a precise and sensitive quantification analysis lies in the error-free detection and analysis of low levels of fluorescence. In order to realize these fundamentals, Montania® 484 is equipped with substantial structural features to meet the requirements and expectations of both diagnostic and research fields. Temperature distribution of +/- 0.1 °C throughout the whole thermal block, a LED light which is capable of exciting with constant intensity during its practically lifelong use, fiber optic translation of every emission read-out and a PMT module system that enables exquisite measurement via physical amplification of each photon’s energy.

Familial Mediterranean fever (FMF) is an autosomal recessive genetic disorder, which occurs commonly in Mediterranean countries causing symptoms such as recurrent acute fever, abdominal pain, joint pain etc. FMF prevalence varies in Turkey locally. However, 0-5 out of every 1000 person have FMF disorder. Marenostrin encoding fever gene (MEFV) is associated with FMF, a gene which is located on the short arm of chromosome 16 (16p13.3), mapped to the 80 kb consisting of 10 exons. Although mutations occur in all exons, clinically the most common mutations are revealed in exon 2, exon 3, exon 5 and exon 10. M694I, M694V, M680I/GA, M680I/GC, V726A, E148Q, R761H, A744S, K695R, P369S, F479L, R202Q, I692del, K695M and M694L are among the most frequently observed mutations of MEVF in various geographical regions.

2019 Novel Coronavirus (2019-nCoV) / SARS-CoV-2, which belongs to the same family as the pathogen that causes severe acute respiratory syndrome (SARS), is first identified as the cause of a respiratory illness outbreak detected in Wuhan, China. For confirmed SARS-CoV-2 infections, symptoms can include fever, cough, and difficulty in breathing ranging from mild symptoms to severe illness and death. Bosphore Novel Coronavirus (2019-nCov) Kits include endogenous internal control for ensuring optimal sample collection. For more accurate & reliable results the kit detects Novel Coronavirus (2019-nCov) using different gene regions as N-gene, S-gene, E-gene and Orf1ab.

Respiratory tract infections are typically divided into upper and lower respiratory tract infections which occur mainly in the nose, throat affecting upper respiratory system, windpipe, airways and lungs affecting lower respiratory system. From clinical point of view; symptoms such as nasal obstruction, nasal discharge, sore throat, cough, irritability occur as upper respiratory tract infections, symptoms such as bronchitis and pneumonia occur as lower tract infections.

Respiratory infections involve bacterial and viral pathogens affecting the upper or lower respiratory tract, and they are one of the major causes of mortality and morbidity, especially among children. Some respiratory infections may only cause mild symptoms such as common cold while some other may result in more serious cases; accounting for around 10 million deaths per year globally. lnvolvement of different viral and bacterial causative agents, complicates the diagnosis of the primary pathogen.