Betalin Therapeutics Ltd. products

Islet transplantation is a widely used cell therapy technique which achieves normoglycemia (normal blood glucose levels) in diabetic patients. However, one of the biggest challenges is early islet cell death, this tends to occur before the transplantation procedure. This is thought to be due to the loss of the islets microenvironment during isolation. The extracellular matrix (ECM, a support network for your tissues and organs) has been shown to be critical for the functioning and viability of islet cells. 

Due to the importance in the ECM in islet function, Betalin have developed a MOM scaffold that used a decelluarized ECM (a process to isolate the ECM from its cells). This aims to mimic the islets natural microenvironment, providing the islet cells with all the required nutrients and gases for survival. The MOM allows a complex network of vascularization, so no islet cell will be starved, which improves the longevity of islet cells.