11 products found
Caprico Biotechnologies, Inc. (CBI) Products
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Clonality - Monoclonal
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Caprico - Model EAPII - Anti-Unconjugated
EAPII (also called TTRAP, TDP2) originally was identified as an interacting partner of oncogene ETS1, a founding member of ets transcription factor, and the cytoplasmic domain of CD40, a member of the tumor necrosis factor (TNF) receptor family. EAPII significantly represses ETS1 transcriptional activity and the synergistic transactivation by ETS1 and AP-1 or by ETS1 and NFκB. EAPII/TTRAP also inhibits the transcriptional activation of NFB induced ...
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Caprico - Model EGFR - Anti Biotin
The clone 528, a mouse monoclonal antibody, specifically reacts with an epitope of the ~170 kDa extracellular protein domain of human epidermal growth factor receptor or commonly known as EGFR. Physiologically EGFR is expressed in the skin, gastrointestinal system, kidney, and other normal tissues as well as aberrantly over expresses in epithelial cancer cells of lung, pancreas, colon, breast, and on the head and neck squamous ...
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Clonality - Polyclonal
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Caprico - Model AP - Donkey Anti-Mouse IgG Antibody
This antibody reacts with the heavy chains of mouse IgG and with the light (kappa and lambda) chains common to most mouse immunoglobulins. The minimal cross-reaction with other species was ensured by pre-adsorption by agarose beads coupled with IgGs from Human, Goat, Rabbit, Bovine, Chicken, Guinea Pig, Syrian Hamster, Horse and Sheep Serum ...
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Biotin - Donkey Anti-Mouse IgG Antibody
This antibody reacts with the heavy chains of mouse IgG and with the light (kappa and lambda) chains common to most mouse immunoglobulins. The minimal cross-reaction with other species was ensured by pre-adsorption by agarose beads coupled with IgGs from Human, Goat, Rabbit, Bovine, Chicken, Guinea Pig, Syrian Hamster, Horse and Sheep Serum ...
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Caprico - Model FITC - Donkey Anti-mouse IgG Antibody
Predictive or prognostic factor in metastatic breast ...
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Conjugation - iFluor 488
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CD13 iFluor - Model 488 - Cell Surface CD13 Antigen
Clone APN1464 recognizes cell surface CD13 antigen, a 150kDa membrane glycoprotein. The CD13 antigen is highly expressed mostly on myeloid-derived hematopoietic cells including granulocytes, monocytes, mast cells, and GM-progenitor cells. CD13 abundantly expresses on most of the malignant cells of myeloid origin such as AML, CML and also on smaller subset of cancer cells of lymphoid origin. Normal lymphocytes, platelets and erythrocytes do not express ...
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Conjugation - iFluor 594
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Anti-HLA-DR iFluor - Model 594 - L243 Reacts With Human HLA-DR Antigen
The L243 reacts with human HLA-DR antigen which is expressed on B lymphocytes, monocytes, macrophages, activated T lymphocytes, activated natural killer (NK) lymphocytes, and human progenitor cells. HLA-DR is also present on thymic epithelium, B lymphocyte dependent areas of spleen and lymph node, and B cell ...
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Excitation Laser - Blue (488nm)
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Anti-IgM PE - Model PE - Mouse Monoclonal Antibody
The clone M-2E6, a mouse monoclonal antibody selectively recognizes the epitope present in the Fab arms (anti- Fdµ) of the surface monomeric IgM molecule on B cells. It reduces the growth of the neoplastic B cells through its intrinsic crosslinking property in vitro. IgM is the first immunoglobulin expressed in the human fetus at around 20 weeks. It plays various important immunological roles in protecting host from the viral and bacterial ...
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Excitation Laser - Green (562nm)
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Anti-IgM - Model PE-Cyanine7 - Mouse Monoclonal Antibody
The clone M-2E6, a mouse monoclonal antibody selectively recognizes the epitope present in the Fab arms (anti- Fdµ) of the surface monomeric IgM molecule on B cells. It reduces the growth of the neoplastic B cells through its intrinsic crosslinking property in vitro. IgM is the first immunoglobulin expressed in the human fetus at around 20 weeks. It plays various important immunological roles in protecting host from the viral and bacterial ...
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Reactivity - African Green
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CD52 - Model FITC - Glycoprotein
Clone CF-1D12 recognizes human CD52, a 21-28 kDa glycoprotein whose C-terminus is glycophosphatidylinositol (GPI) anchored within the membrane. It is also known as Cambridge pathology antigen 1 (CAMPATH-1). Binding of CF-1D12 with CD52 induces a potent complement-mediated cytolytic immune response of matured lymphocytes. It is widely expressed on the surface of thymocytes and mature lymphocytes, on monocytes, dendritic cells, eosinophils and epithelial ...
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Status - ASR
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Model Anti-HLA-DR APC-Cyanine7 - Mouse Monoclonal Antibody
The clone L243, a mouse monoclonal antibody, recognizes a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain known as human HLA-DR antigen. HLA-DR is widely expressed on monocytes, macrophages, activated T and B lymphocytes, activated natural killer (NK) cells, and human progenitor cells. HLA-DR is also present on thymic epithelium, B-lymphocyte-dependent areas of spleen and lymph node, and ...