CC Diagnostics products

CC Diagnostics collaborates with the DNA methylation ResearchGroup at the UMCG (heade by Dr G. Bea A. Wisman, molecular biologist and external scientific advisor for CC Diagnostics, and by Prof dr. Ed Schuuring, clinical scientist in molecular pathology). During their fundamental research in the last 15 years, this group has identified and clinically-validated numerous CIN2+-specific tumor-suppressor genes deregulated by DNA hypermethylation. They reported that DNA methylation status of these genes has predictive value whether or not cervical cancer or its precursors are present in cervical scrapings. Therefore, these CIN2+-specific methylation markers might be of relevance in the early detection of cervical cancer. The methylation assay consists of a balanced combination of the probes and primers of the three best performing methylation markers in a multiplex test kit.