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Introduction
Microarray printing technology has revolutionized the field of genomics and proteomics, and its application in glycobiology is no exception. Glycobiology, the study of carbohydrates and their biological functions, relies heavily on the ability to analyze large-scale carbohydrate interactions. Microarray printing in glycobiology enables the precise and high-throughput analysis of carbohydrate-protein interactions, glycan structures, and cell surface receptors. This article
Sugar nucleotides are key molecules in the biosynthesis of glycans, which are carbohydrate chains found on the surface of cells or in the bloodstream. These molecules play a critical role in a wide range of biological processes, including cell signaling, protein folding, and immune responses. In this article, we will delve into the structure and synthesis of sugar nucleotides, and explore their importance in glycobiology.
The Structure of Sugar Nucleotides
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Carbohydrates are one of the essential macromolecules that play a crucial role in the functioning of living organisms. They serve as a primary source of energy and are involved in various biological processes. The synthesis of carbohydrates is a complex and fascinating process that occurs in living organisms, allowing them to produce and utilize these vital molecules. In this blog post, we will explore the process of carbohydrate synthesis, its significance, and its implications in the world
Introduction
Glycans, also known as carbohydrates, are complex molecules that play a crucial role in various biological processes. They are involved in cell signaling, immune responses, and cell adhesion, among other functions. Glycan arrays have emerged as powerful tools for studying the interactions between glycans and other molecules. In this blog post, we will delve into the world of glycan arrays, exploring what they are, their applications, recent research advances,
Carbohydrates, the ubiquitous energy source for life, are intricate molecules that play a fundamental role in various biological processes. Their synthesis is a testament to nature's ingenuity.
Carbohydrate synthesis, a subfield of organic chemistry, delves into the intricate methods of constructing these essential molecules. It encompasses a wide spectrum of techniques, from the simple formation of monosaccharides, the building blocks of carbohydrates, to the elaborate a
What is Cocklebur?
Xanthium strumarium is a flowering plant belonging to the Asteraceae family. It is an annual herb known for its rough, oval spines covered in hooked spines. These burrs easily attach to clothing, fur, and feathers, allowing the plant's seeds to disperse over long distances. It is considered a noxious weed in some areas due to its toxicity and impact on agriculture. The seeds and seedlings of this plant contain a toxic substance called atratyloside, which can be harmf
Previously, it was thought that glial cells, which support neuronal activity, metabolize most of the glucose in the brain. However, by using induced pluripotent stem cells, the researchers found that neurons were able to take up glucose and process it into smaller metabolites. In mice, normal function of neurons depends on glycolysis. The findings could help develop new treatments for neurodegenerative diseases such as Alzheimer's and Parkinson's, and help understand how to keep the brain hea
Streptococcus pneumoniae is the leading cause of pneumonia, sepsis and meningitis. Collectively, these infections are a leading cause of morbidity and mortality in older adults and young children. To fight these deadly infections, a pneumococcal vaccine is given to stimulate the production of antibodies against CPS. However, bacteria can manipulate their CPS structure to evade these antibodies. This biochemical warfare results in the production of more than a hundred CPS by S. pneumoniae, add
Hundreds of millions of people suffer skin tissue damage every year, including accidental injury, surgical injury, chronic ulcer, etc., and severe cases may lead to amputation or even life-threatening. Suturing is currently the preferred method for clinically closing wounds. However, wound suturing takes a long time during the operation, and removing the stitches will cause secondary damage to the tissue, and easily lead to risks such as scar hyperplasia, contracture, and infection. The inven
When we feel uncomfortable, we tend to eat less, drink less, and exercise less. This is not unique to humans—most animals reduce these three behaviors when fighting infection.
Recently, a new study pinpoints clusters of neurons that control these responses (uncomfortable behavior). By provoking immune responses in mice, the researchers demonstrated that specific cell populations in the brainstem could effectively induce three suggestive uncomfortable behaviors. In a
