i-FACTOR Bone Graft facilitates the ingrowth of bone by promoting the migration of mesenchymal stem cells and other progenitor cells from surrounding tissue.
The pinnacle of scientific evidence is the Level I study. i-FACTOR Bone Graft is one of a small group of bone grafting technologies that is supported by Level I evidence. i-FACTOR Bone Graft was evaluated in a 319-patient, prospective, randomized, controlled, multi-center clinical trial assessing its safety and efficacy compared to standard-of-care (autograft). Patients underwent anterior cervical discectomy and fusion (ACDF) and received either i-FACTOR Bone Graft or local autograft in a cortical allograft...
Due to poor bone stock in the elderly, a non-instrumented fusion is commonly performed in Scandinavia when instability is present. Allograft bone is often used as graft extender with consequent low fusion rates. The aim of this study was to evaluate the performance of i-FACTOR against Bone Bank Allograft.