CoaguSense Inc. articles

Discovery
In the late 19^th century, researchers attempted to produce a drug with a hemostatic effect  by injecting a peptone and inducing the release of an anticoagulant. The water-soluble substance isolated from the liver was heparin, but no one knew it at the tim

What do rat poison and anticoagulation medicine have in common? As often happens in scientific discovery, research follows a twisted route to the most effective remedy.

Introduction
Oral anticoagulant therapy (OAT) using warfarin (Coumadin) has surged in recent years due to an increased number of indications and its demonstrated effectiveness. The primary means of monitoring the response to warfarin is the Prothrombin Time (PT) test, which is measured in seconds. The increased use of OAT has led to the development of point-of-care (POC) portable monitoring devices designed to use a capillary sample of whole blood for PT determination.</