Creative Biogene-Mitochondrial Research products

Tissue Mitochondria Extraction Kit is used to quickly and conveniently isolate mitochondria from animal tissues.The purity of the mitochondria obtained by using this kit is relatively high, and most of the mitochondria obtained by separation contain complete inner and outer membranes, and have the physiological functions of mitochondria. Therefore, the mitochondria isolated by this kit can be used for research on the physiological functions of mitochondria.The mitochondria separated by this kit can also be lysed by the mitochondrial lysate in the kit or other appropriate lysates for protein analysis such as SDS-PAGE, Western, and two-dimensional electrophoresis.

The mitochondria diluted or preserved in this mitochondrial storage solution can ensure the integrity of the mitochondria and will not damage the mitochondrial structure. Diluted or preserved mitochondria can be used for subsequent intact mitochondrial function or enzyme activity studies

This kit is used for distinguishing between healthy and apoptotic cells by detecting the changes in the mitochondrial transmembrane potential.

This kit is used for detecting cytochrome c translocation from mitochondria into cytosol during apoptosis.

The oxidative stress reactive oxygen species (ROS) high-quality fluorescence measurement reagent for living tissues is a kind of membrane-permeable fluorescent dye CM-H1DCFDA, which produces fluorescence under the condition of tissue oxidative damage. A classic technical method for quantitatively detecting the generation and increase of reactive oxygen species in the tissue. It can be used for research on apoptosis, signal transmission, aging, metabolism and nutrition. The product is strictly sterile, ready to use, easy to operate, in vivo detection, and has stable performance.

This kit is used to screen for human GLS1 inhibitors. Glutamine is hydrolyzed by glutaminase to form glutamate and ammonia. In the presence of a chromogenic agent and enzyme mixture, glutamate is converted from a non-fluorescent probe to a fluorescent product by an enzymatic reaction. The well known glutaminase inhibitor - CB-839 is provided as an inhibitor control.

This product provides a convenient and rapid fluorescence assay for the detection of mitochondrial autophagy. Our specific dyes accumulate in intact mitochondria, which then exhibit only weak luminescence. When Mitophagy is induced, the specific dye can emit high bright fluorescence.

This kit can label mitochondria in live cells with red fluorescence. The kit uses a proprietary dye that can accumulate in mitochondria based on the mitochondrial membrane potential gradient. The mitochondrial indicator is a hydrophobic compound that can easily penetrate intact living cells and become trapped in mitochondria after entering the cell. The fluorescent mitochondrial indicator remains in the mitochondria for a long time. This key feature significantly improves dyeing efficiency. It can be easily applied to various fluorescence platforms, such as microplate analysis, immunocytochemistry and flow cytometry. It is suitable for a variety of studies, including cell adhesion, chemotaxis, multidrug resistance, cell viability, apoptosis and cytotoxicity.