16 Articles found
Creative Biostructure Articles
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Shining a Light on Drug Delivery: The Rise of Fluorescent Liposomes
Imagine tiny spheres, smaller than a red blood cell, glowing as they navigate the labyrinthine corridors of the human body. These aren't fireflies, they're fluorescent liposomes, a cutting-edge tool in the world of drug delivery and biomedical ...
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Drug-Loaded Liposomes: Tiny Spheres with Big Potential
Imagine tiny bubbles, smaller than a red blood cell, carrying powerful medicines directly to diseased cells. This isn't science fiction, it's the cutting edge of drug delivery with drug-loaded liposomes. What are liposomes? Liposomes are ...
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Nano-Flow Cytometry: A Revolutionary Tool for Biomedical Research
Nano-flow cytometry is a revolutionary technology that has the potential to transform early disease detection and diagnosis. Nano-flow cytometers are able to detect and analyze individual nanoparticles, including extracellular vesicles and viruses, ...
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High-resolution structure of a key bacterial enzyme: Aid in the fight against antibiotic resistance
A team of scientists from around the world, including from Trinity College Dublin, has obtained high-resolution structural insights into a key bacterial enzyme, which may help chemists design new drugs to inhibit it, thereby inhibiting ...
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How Much Do You Know about Fluorescence Resonance Energy Transfer?
Fluorescent substance and fluorescent labeling technology The compounds upon which fluorescent labeling depends are called fluorescent substances. Fluorescent substances refer to compounds with a conjugated double bond system chemical structure, ...
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Nature: 3D structures of proteins involved in genome editing
Gene editing is one of the latest breakthroughs in biology. The well-known CRISPR-Cas gene editing system confers immunity against foreign DNA to prokaryotes (organisms lacking a cell nucleus). Since the discovery of CRISPR gene editing technology, ...
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Understanding the Structure of the HIV Protein May Lead to New Treatments
Scientists from Rutgers University and Salk Institute have determined the molecular structure of HIV Pol polyprotein, which plays a key role in helping the virus spread itself and systemically. This finding may stimulate new treatments for more than ...
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A Small Protein May Help People with Epilepsy and Other Diseases
For the first time, scientists have elucidated the structure of GABA transporter 1 (GAT-1) using cryo-electron microscopy. The discovery could lead to better new treatments for neurological disorders such as anxiety, autism spectrum disorder, ...
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Near-atomic-level Details of Cancer Proteins with the Help of Molecular Cages Revealed
Sandwiching the wobble protein between two other layers allowed scientists to get the most detailed picture of a protein that is key to the spread of acute myeloid leukemia. Acute myeloid leukemia (AML) afflicts more than 20,000 Americans each year, ...
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How Can Liposomes Be Used in Cosmetics?
Liposomes have a phospholipid bilayer structure similar to cell membranes. Liposomes are closed ultramicrospheres, similar to an organelle-free artificial cell (only with cell membranes). The artificially manufactured liposome structure is also very ...
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Nipah virus glycoprotein structure suggests therapeutic strategies
Recent molecular discoveries have provided new details on how Nipah and Hendra viruses attack cells, and the immune responses that fight back against this attack. The findings point to a multi-pronged strategy for preventing and treating these ...
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How Hyaluronic Acid Promotes Pancreatic Cancer Cell Growth Revealed
Hyaluronic acid is known to be present in pancreatic tumors. However, in a new study, researchers from the University of Michigan Roger Cancer Center and the University of Pennsylvania found that hyaluronic acid also acts as a food for cancer cells. ...
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New Drug Discovery Tool that Can Screen More Than 11 Billion Compounds Found
There are docking stations called receptors on the surface of our cells. Various compounds ranging from caffeine and dopamine to heroin, tetrahydrocannabinol (THC) and lysergic diethylamine (LSD) all bind to these receptors. Indeed, G ...
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The Mode of Action of Basic Proteins Involved in Cancer and Alzheimer's Disease Found
These proteins belonging to the HAT family are essential for life because they transport amino acids to the cell membrane. Although members of the family are nearly identical, they selectively transport certain amino acids. This specificity ...
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Nature: Structure-based classification of tauopathies
Abnormal accumulation of misfolded tau in filaments is characteristic of many neurodegenerative diseases—precisely for this reason, these neurodegenerative diseases are collectively referred to as tauopathy. The Michel Goedert team and the ...
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Researchers Prepared New Tools for the Production of Exosome Drug Carriers
Recently, Yang Hui, a researcher at Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, developed a nanofluidic chip technology to achieve high-throughput preparation of exosome drug carriers and experimentally verify the ...