Darnitsa Group products

Mineral supplements. Calcium drugs. Calcium gluconate. Calcium gluconate is a calcium salt of gluconic acid containing 9% calcium. Calcium ions are involved in nerve impulse transmission, smooth and skeletal muscle contraction, myocardial functioning, blood clotting processes; they are required for bone tissue formation, and normal functioning of other systems and organs.

Aciclovir is a synthetic analogue of purine nucleoside with in vivo and in vitro inhibitory activity against human herpes virus, including herpes simplex type 1 and 2, varicella zoster virus and herpes zoster, Epstein-Barr virus, and cytomegalovirus. In cell culture, aciclovir is most effective against herpes simplex type 1 and 2, and then, in decreasing order of activity, against varicella zoster virus and herpes zoster, Epstein-Barr virus, and cytomegalovirus.

Valsartan is an active specific angiotensin II receptor antagonist for oral use. It selectively influences AT1 subtype receptors responsible for the known effects of angiotensin II. Elevated plasma angiotensin II levels after AT1 receptor blockade by valsartan can stimulate the unblocked AT2 receptor that balances the effect of the AT1 receptor. Valsartan does not show any partial agonist activity against the AT1 receptor, but has much greater (approximately 20,000 times) affinity for the AT1 receptor than for the AT2 receptor.

Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme that converts 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate, a precursor of cholesterol. The primary site of action of rosuvastatin is the liver, the target organ for cholesterol lowering. Rosuvastatin increases the number of hepatic low-density lipoprotein (LDL) receptors on the cell surface, enhancing uptake and catabolism of LDL and it inhibits the hepatic synthesis of very low-density lipoproteins (VLDL), thereby reducing the total number of VLDL and LDL particles.

Drugs affecting the digestive system and metabolic processes. Biogenic stimulant. It has an adaptogenic and general tonic action.