10 products found
GW Pharmaceuticals plc Products
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Healthcare Professionals - Research & Trials - Therapeutic Areas
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GW - Spasticity and Post-Traumatic Stress Disorder PTSD Treatment
Our proprietary complex botanical mixture, called nabiximols (Sativex® outside of the U.S.) is an oromucosal spray of a formulated cannabis extract that contains the principal cannabinoids delta-9-tetrahydrocannibinol (THC) and cannabidiol (CBD) as well as specific minor cannabinoids and other non-cannabinoid components. GW developed nabiximols to be administered as an oromucosal spray, whereby the active ingredients are absorbed in ...
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GW - Autism Spectrum Disorder Treatment
Many of the childhood-onset intractable epilepsy conditions within the expanded access program share considerable overlap with ASD and these conditions often fall within the orphan disease space. Initial clinical observations from treating physicians suggest a potential role for cannabinoids in addressing problems associated with ASD such as deficits in cognition, behavior, and ...
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GW - Schizophrenia Treatment
Schizophrenia is a chronic disease that manifests through disturbances of perception, thought, cognition, emotion, motivation and motor activity. Over a lifetime, about 1% of the population will develop ...
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GW - Neonatal Hypoxic-Ischemic Encephalopathy Treatment
NHIE is acute or sub-acute brain injury due to asphyxia caused during birth resulting from deprivation of oxygen during birth (hypoxia) as a result of a sentinel event such as ruptured placenta, parental shock and even increased heart rate. Hypoxic damage can occur to most of the infant’s organs, but brain damage is the most serious and least likely to heal, resulting in encephalopathy. This can later manifest itself as either mental retardation ...
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Healthcare Professionals - Research & Trials - Cannabinoid Compounds
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GW - Phytocannabinoids, Endocannabinoids and Synthetic Cannabinoids
The term "cannabinoid" has different meanings. Cannabinoids were originally defined as a group of C21 compounds uniquely produced by the cannabis plant. Subsequent development of synthetic cannabinoids and the discovery of natural cannabinoids in the body (“endocannabinoids”) has somewhat blurred this definition. The molecules derived from the plant itself are therefore now termed “phytocannabinoids”. Synthetic cannabinoids are ...
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GW - Phytocannabinoid Compounds
Naturally occurring cannabis contains a group of chemical compounds not found in other plants known as cannabinoids. Over 80 different cannabinoids have so far been identified but the role and importance of many of these has yet to be fully understood. GW is researching a large number of cannabinoids, each of which has different effects and ...
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GW - Natural Cannabinoids (endocannabinoids)
The discovery of the cannabinoid receptors led to the demonstration of the existence of the body’s own natural cannabinoids endocannabinoids), the most important of which are arachidonoyl-ethanolamide (anandamide), 2-arachidonoyl glycerol (2-AG) and arachidonyl glyceryl ether (noladin ether). This remains a highly dynamic ...
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Epilepsy - Cannabidiol Oral Solution
GW is committed to developing new medicines to treat rare, treatment-resistant epilepsy conditions where there are limited or in some cases, no approved treatment ...
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Sativex - Delta-9-Tetrahydrocannibinol and Cannabidiol
Sativex® (delta-9-tetrahydrocannibinol and cannabidiol in the EU; nabiximols in the US) is an oromucosal spray of a formulated cannabis extract that contains the principal cannabinoids delta-9-tetrahydrocannibinol (THC) and cannabidiol (CBD), as well as specific minor cannabinoids and other non-cannabinoid components. We developed Sativex® to be administered as an oromucosal spray, whereby the active ingredients are ...
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Sativex - Model nabiximols - MS Spasticity
Sativex® (nabiximols) has been developed as a treatment for the relief of symptoms in patients with moderate to severe spasticity due to multiple sclerosis (MS) that has not been adequately treated with currently used therapies. Sativex® is not approved in all countries. Please consult with your doctor if you would like more ...