Harvard Apparatus Regenerative Technology, Inc. formely known as Biostage, Inc. products

Following extensive research and development, Biostage has evolved its technology to optimize the interaction of mesenchymal stem cells seeded on a biocompatible scaffold. Preclinical studies suggest that, once implanted, the scaffold seeded with the patient’s own cells signals the stem cell niche to guide the regeneration of a biological structure.

Cellspan Tracheal Implants may allow for the safe reconstruction of any portion of the trachea, potentially restoring its functional integrity. Proof-of-concept was confirmed in man in an earlier generation tracheal product showing that an electrospun scaffold seeded with the patient’s own cells can form a patent airway.

Cellspan Bronchial Implants may enable the surgeon to preserve the lung and repair the bronchus following surgical resection—without debilitating outcomes and complications.

Cellspan Esophageal Implants may offer improved outcomes for patients by potentially simplifying surgical techniques to reduce post-operative complications, improve quality of life and enable regeneration of the patient’s own esophagus.