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Icosagen AS products

Proteins

SARS-CoV-2 Trimeric Spike C.37 (lambda)

Protein contains amino acids 14-1211 and following mutations: G75V, T76I, del 246-252, L452Q, F490S, D614G, T859N. Plus two extra amino acids (AS) in N-terminus, trimerization domain and His-6 tag at C-terminus, GS linker between protein and trimerization domain and GSG linker between trimerization domain and His-tag. Furin cleavage (RRAR) site between Spike S1 and S2 is mutated (GSAS).

SARS-CoV-2 Trimeric Spike Californian B.1.429.1

Protein contains amino acids 14-1211 and following mutations: W152C, L452R, D614G, Q677H. Plus two extra amino acids (AS) in N-terminus, trimerization domain and His-6 tag at C-terminus, GS linker between protein and trimerization domain and GSG linker between trimerization domain and His-tag. Furin cleavage (RRAR) site between Spike S1 and S2 is mutated (GSAS).