6 Articles found
Indee Labs Articles
-
The Problem with Gene-Modified Cell Therapy Manufacturing
Gene-modified cell therapies (GMCTs) represent the most effective therapeutic platform for many patients with advanced diseases including relapsed and refractory leukemia, non-Hodgkin lymphoma, and other blood cancers [1]. Specifically, chimeric ...
-
The Limitations and Challenges of Cancer Therapies
Considerable investment into cancer research has led to the development of remarkable new therapies, which have greatly improved therapeutic outcome for the countless individuals diagnosed with cancer. Until recently, almost all therapies that were ...
-
Indee Lab’s CRISPR Delivery Technology for Affordable Immunotherapies
Ryan Pawell is the founder and CEO of Indee Labs, a Berkeley biotech. The mission of Indee Labs is to use microfluidic vortex shedding as a scalable method to deliver CRISPR reagents into cells for developing affordable cell and gene therapies ...
-
New Cell Contenders in the CAR Field (Part 2)
Why do we need new cell contenders in the CAR field? Well, different CAR immune cells have different advantages and sometimes unique challenges or limitations. So, we began our discussion of alternative CAR-cell types with ...
-
New Cell Contenders in the CAR Field (Part 1)
Chimeric antigen receptor T-cells (CAR-T) are one of the first clinically approved therapies to take full advantage of the most significant advancements in immunology and genetic engineering. The resulting therapeutics have been ...
-
Saving Us from Ourselves: Harnessing the Power of CAR-T to Combat Autoimmunity
What is autoimmune disease? Autoimmune disease a condition in which the body’s immune system mistakenly attacks the body itself. Thus far, more than 80 different autoimmune diseases have been identified, with some of the most prevalent ...