Inflammatix, Inc.
Inflammatix is reimagining diagnostics by developing rapid tests that read the immune system to resolve major clinical and public health challenges. Our initial focus is on acute bacterial and viral infections, and sepsis. This test has not yet been cleared or approved by the FDA, nor has it been CE marked. Inflammatix is establishing partnerships with diagnostic instrument, companion therapeutic and commercial distribution companies across the globe.
Company details
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- Business Type:
- Manufacturer
- Industry Type:
- Medical Equipment
- Market Focus:
- Globally (various continents)
- Year Founded:
- 2016
Our Mission
At Inflammatix, we are reimagining diagnostics
Inflammatix will create and commercialize best-in-class host-response diagnostics to resolve major clinical and public health challenges.
Better patient care is at the core of what we do. We achieve better patient care through our innovative approach to developing diagnostics–our tests read the patient’s immune system to help us understand the cause of infection and the degree of its severity. Armed with this knowledge, the clinician can treat the patient appropriately and within minutes.
Precision medicine on demand
There is a critical unmet need for quickly and accurately characterizing infections in patients who are acutely ill. Our expert bioinformatics and assay development teams are building a host response-based diagnostics pipeline that includes tests for acute infection and sepsis, emerging infectious diseases, autoimmune diseases, tropical infections, transplant rejection and other conditions.
We are initially focused on developing tests for acute bacterial infections, viral infections, and sepsis based on patent-pending biomarkers exclusively licensed from Stanford University.
Our Approach
Our approach to developing host response-based diagnostic tests has yielded remarkable results to date
Focus on what clinicians want
Every test should be built with a physician end-user in mind. Our team is physician-led, ensuring that development starts with the question of whether a test could be clinically actionable, and whether it fits into workflow. Our test for sepsis was built to answer a critical clinical gap: physicians usually guess about whether or not a patient needs antibiotics. Current pathogen-focused diagnostic methods fail to answer this question because they frequently miss infections that haven’t spread to the bloodstream. Thus, we focused on using the immune response to infections to answer to key clinical action items in the evaluation of an acutely ill patient: (1) does the patient need antibiotics, and (2) what level of care is required? These questions are best answered by ‘reading’ the immune response, rather than looking directly for a pathogen as a ‘needle in a haystack’.
Embrace heterogenous data in product development
Embrace heterogenous data in selecting and analyzing cohorts to study. Acute infections can be remarkably clinically diverse: kids and adults, inpatients and outpatients, in different settings around the world. We wanted to build a test that would work in every environment. We thus embrace this clinical heterogeneity by analyzing multiple cohorts that are diverse in their population, sample types, assays used and other factors. Our robust statistical pipeline allows us to find reproducible signal in the ‘noise’ of multiple datasets. Although this is a hard challenge, our discovery methods ensure that the diagnostics we find are generalizable to new populations.
Validate externally
Validate on multiple, independent and diverse cohorts. Trustworthy tests must demonstrate robust performance in independent, blinded multi-center studies.