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Recombinant protein drugs refer to protein products that originate from animals and plants and are developed through biotechnology research. These protein drugs exhibit certain biological activity and can prevent, diagnose, and treat diseases in humans, animals, and plants. Compared with small molecular drugs, recombinant protein drugs offer advantages such as high activity, high specificity, and low toxicity, and are therefore favored by researchers. At present, recombinant protein drugs are
Antibody drugs are a kind of drugs that treat diseases through artificially synthesized antibodies, achieving therapeutic purposes by specifically binding with target molecules. Common types of antibody drugs include monoclonal antibodies, artificially synthesized antibody fragments, immunotoxins, antibody-drug conjugates, etc. Antibody drugs have shown remarkable therapeutic effects in the treatment of various diseases, such as cancer, autoimmune diseases, inflammatory diseases, immune regul
Recombinant protein vaccines are vaccines produced using genetic engineering technology. The principle is to clone one or several antigen genes of a pathogen into host cells, causing them to express the corresponding antigen protein. These proteins are then extracted for use in the vaccine. These vaccines can effectively stimulate the immune system to respond to specific pathogens, thereby providing protective effects. Since the production of recombinant protein vaccines involves the growth a
Peptide drugs are bioactive protein fragments composed of short chains of amino acids. Due to their high efficiency, specificity, and relatively low toxicity and immunogenicity, they occupy an important position in modern medicine and drug development. They have shown great potential in treating various diseases, such as cancer, autoimmune diseases, infectious diseases, and metabolic disorders. However, to ensure the safety and efficacy of these drugs, strict quality control and characterizat
Collagen is a crucial structural protein, widely presenting in human skin, bones, tendons, ligaments, and other tissues. It's essential for maintaining the structural integrity and function of tissues. The measurement of collagen can help researchers and physicians understand the pathological process of related diseases (such as osteoporosis, arthritis, skin aging etc.), and also aid in drug development and other biomedical research.
The measurement of coll
Antibody drugs are a type of drugs that treat diseases through artificially synthesized antibodies, which bind specifically to target molecules for therapeutic purposes. Common types of antibody drugs include monoclonal antibodies, artificially synthesized antibody fragments, immunotoxins, and antibody-drug conjugates, etc. Antibody drugs have shown significant therapeutic effects in the treatment of various diseases such as cancer, autoimmune diseases, inflammatory diseases, immune regulatio
Collagen is an important structural protein that is widely found in various biological tissues, such as skin, bones, tendons, and blood vessels. Accurate determination of collagen content is very important for biomedical research, disease diagnosis and quality control of related products. Here are some commonly used methods for determining collagen content.
Chromatography
High-performance liquid chromatography (
Recombinant protein vaccines are vaccines prepared by expressing and purifying the antigen proteins of pathogens in engineered cells (such as bacteria, yeast, mammalian cells, and insect cells) using genetic engineering technology. Compared with other types of vaccines, recombinant protein vaccines are more costly but have significantly better safety profiles. The intrinsic fluorescence of a protein mainly originates from the aromatic amino acids in its structure, such as tryptophan, tyrosine
Recombinant protein drugs are protein-based therapeutic drugs which are produced by using DNA recombination technology or other biotechnological methods. These drugs include cytokines, peptide hormones, recombinant enzymes, monoclonal antibodies, and fusion proteins. Compared to traditional low-molecular-weight synthetic drugs, recombinant protein drugs have advantages such as high specificity, low toxicity, and significant therapeutic effects. Additionally, recombinant protein drugs can be u
Optical Rotatory Dispersion (ORD) and Circular Dichroism (CD) are two important techniques widely used in the study of biomolecules, particularly the structure of proteins and nucleic acids. These techniques are based on the interaction of molecules with light, specifically how the molecules affect plane-polarized light that passes through them.
Optical Rotatory Dispersion
1. Fundamentals
