Onda Corporation articles

Abstract
A large transducer to generate high intensity focused ultrasound (HIFU) for surgery via tissue ablation is described. Designed to address the need for therapeutic applications into deep tissue, the device operates at 1.25 MHz. In order to increase focus-to-entrance intensity ratios, the design was optimized to have a natural focal distance of 10 cm at fA.0. Variable focus is achieved by phasing the array, and particular care was exercised to maximize the range o

Abstract

A robust needle hydrophone has been developed for HIFU transducer characterization and reported on earlier [1]. After a brief review of the hydrophone design and performance, we demonstrate its use to characterize a 1.5 MHz, 10 cm diameter, F-number 1.5 spherically focused source driven to exceed an intensity of 1400 W/cm at its focus. Quantitative characterization of this source at high powers is assisted by deconvolving the hydrophone`s cal

Background - Limitations of coronary thrombolysis include the time to reperfusion, patency rate, and bleeding. We evaluated the use of noninvasive transcutaneous ultrasound to augment coronary thrombolysis.

Methods and Results - In 24 dogs, a thrombotic occlusion of the left anterior descending coronary artery was induced and documented by 12-lead ECG and coronary angiography. After $60 minutes of occlusion, tissue-type plasminogen activator (t-PA; 1.