4 products found
Pluristem Therapeutics Inc. Products
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PLacental eXpanded (PLX) Products
PLacental eXpanded (PLX) cells are placenta-derived, mesenchymal-like adherent stromal cells that are expanded ex vivo and are designed to be administered to patients without the need for tissue or genetic matching. These cells release soluble biomolecules, such as cytokines, chemokines and growth factors, which act in a paracrine and endocrine manner to facilitate healing of damaged tissue by stimulating the body’s own regenerative mechanisms.
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Pluristem - Model PLX-PAD - Cells Exhibit Regenerative Potential
PLX-PAD cells exhibit regenerative potential due to their capacity to release factors in response to chemical distress signals from tissues that have been damaged by muscle trauma or inflammation. These therapeutic factors trigger the body’s repair mechanisms and stimulate tissue renewal, differentiation and modulation of immune-mediated inflammation. PLX-PAD cells also modulate the immune system, which plays a central role in the body’s ...
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Pluristem - Model PLX-R18 - Cells Release Combination of Therapeutic Protein
PLX-R18 cells release a combination of therapeutic proteins in response to a damaged or poorly functioning hematopoietic system; this system creates the blood cells that protect us from infection, uncontrolled bleeding and anemia. PLX-R18 is currently in a Phase I clinical trial to treat incomplete hematopoietic recovery following Hematopoietic Cell Transplantation (HCT) ...
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Pluristem - Model PLX-Immune - Cells for Tumor Necrosis Factor Alpha (TNF-a) and Interferon-Gamma (IFN-g)
PLX-Immune are cells that have been induced with tumor necrosis factor alpha (TNF-a) and interferon-gamma (IFN-g), to transiently alter their secretion profile. The product has been evaluated in pre-clinical studies and a peer-reviewed article in the journal Scientific Reports, from Nature, was published which examined the effect of the cells in over 50 lines of human cancerous cells. The results showed that ...
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Science & Technology
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Pluristem - Point-Of-Care Thawing Device
Our convenient, automated thawing device, for use by clinicians at point of care, offers a reliable and simple thawing method that can safeguard the integrity of the supply chain. This is key to maintaining the potency and consistency of a cell product, because, unlike many traditional drugs, cell therapies must be thawed before being administered to a patient. However, the most commonly used thawing procedure can stress the cells and even result in cell ...