Profusa, Inc.
Profusa´s mission is to make our body´s chemistry easily accessible to improve health and wellness. We are dedicated to becoming a leader in the development of real-time biosensors that provide unprecedented insights into our overall health status. Welcome to Profusa, Inc. We are leading the development of a new generation of biointegrated sensors that empowers the individual with the ability to monitor their unique body chemistry in unprecedented ways to transform the management of personal health and disease. Our technology enables the development of bioengineered sensors that become one with the body to detect and continuously transmit actionable, medical-grade data for personal and medical use.
Company details
Find locations served, office locations
- Business Type:
- Software vendor
- Industry Type:
- Medical Monitoring
- Market Focus:
- Internationally (various countries)
About Us
Profusa’s first clinical offering in the European Union, the Lumee™ Oxygen Platform, is designed to report reliable tissue oxygen levels at various regions of interest, both acutely and long-term. The Lumee™ Oxygen Platform has been designed for use in applications where monitoring of compromised tissue is beneficial, such as peripheral artery disease that results in narrowing of blood vessels and reduced blood flow to the lower limbs; chronic wounds (diabetic ulcers, pressure sores) that do not heal properly; and reconstructive surgery.
Our Vision
Profusa is pioneering tissue-integrating biosensors for continuous monitoring of body chemistries.
Breaking the Biocompatibility Barrier
Profusa’s unique bioengineering approach overcomes the largest hurdle in long-term use of biosensors in the body: the foreign body response. Approximately 5 mm long and 500 microns in diameter, each tiny biosensor is a soft, flexible fiber designed to be biologically compatible with the body’s tissues for continuous monitoring, while overcoming the effects of local inflammation or rejection. (Note: The finger is shown for size comparison.)
Tissue-integrating Scaffold
Providing medical-grade data, the biosensor is made of a porous “smart gel” that mimics the 3D microenvironment of cells. The smart gel is linked to a light-emitting molecule that emits a fluorescent signal in the presence of one or more body chemicals such as oxygen, glucose, lactate, or other biomarker.
Optical Reader
Adhered to the skin’s surface or held by hand, a separate optical reader is used to read the fluorescent signal from the embedded biosensor. The reader sends excitation light through the skin to the biosensor, which then emits fluorescent light proportional to the amount of biochemical measured.
Adaptable Form Factor for Consumer and Medical Applications
Profusa’s technology platform enables the development of biosensor systems with a variety of form factors serving consumer as well as medical applications for continuous monitoring of body chemicals. Results from the optical reader are designed to be transmitted to a smart phone application that allows the user to make actionable decisions, from improving their general health and well-being, to taking their athleticism to another level, or managing a chronic disease such as diabetes or COPD. Data can be shared securely via HIPAA-compliant digital networks with healthcare providers and public health analysts conducting longitudinal studies.