Quidel Corporation products

Worldwide, Campylobacter species are the most common cause of bacterial gastroenteritis, with 400-500 million cases of diarrhea each year.¹ Infants in developing countries are at even greater risk, as are travelers to those countries.² Campylobacter–associated gastroenteritis is estimated to affect nearly one million people a year in the U.S.³ In approximately 1 of 1000 cases, Campylobacter jejuni is closely linked to the subsequent development of Guillian-Barre Syndrome, an acute auto-immune paralysis.⁴ C. jejuni infection has also been associated with reactive arthritis in both children and adults.^4,5 When individuals with severe symptoms of gastroenteritis seek medical help, the clinician is faced with multiple possible causes that can present with similar clinical features (e.g., diarrhea, nausea, vomiting, fever, abdominal pain) but that require very different, often conflicting, types of treatment.⁴

Chlamydia is a genus of bacterial pathogens that includes Chlamydia trachomatis and Chlamydia pneumonia. C. pneumonia is a common cause of atypical pneumonia and C. trachomatis causes the most common sexually transmitted disease.

Acute conjunctivitis (adenoviral conjunctivitis or “pink eye”) is an inflammation that can be caused by infections from bacteria or viruses. Pink eye can also be caused by allergy, eye injury, or reaction to medication.

Human Adenoviruses are a large group of DNA viruses that were first isolated from an adenoid gland in 1953.¹ There are over 50 different serotypes.² Adenovirus infections are often asymptomatic, but can cause a wide range of illnesses and symptoms such as: ²

Bordetella is a family of small gram-negative bacterial pathogens that cause respiratory tract infections in humans and animals.¹ Nine species of Bordetella have been identified to date, but Bordetella pertussis causes most of the human disease and only three additional members, B. bronchiseptica, B. parapertussis, and B. holmesii have been associated with respiratory infections in humans. B. pertussis causes whooping cough, a highly contagious respiratory tract infection with characteristic severe coughing episodes. The incubation period is on average 7-10 days and the disease follows a prolonged course consisting of three stages: (1) persistent runny nose (2) paroxysmal coughing, and (3) convalescence.²