Schedio products

Operator & Product Protection Systems

High Containment Isolators

Discover Our Advanced High Containment Isolators: Customized Solutions for the Safe Handling of Highly Potent APIs. The pharmaceutical industry is constantly evolving, facing the challenge of keeping up with the growing demand for highly potent APIs (HPAPI). This increase in demand requires more stringent safety measures to protect operators from potential hazards, and high containment equipment is essential in this context. Micronization, a process that generates ultra-fine particles, presents significant containment challenges due to the potential health risks these particles pose. Developing effective safety measures to address these risks is complex. Each year, operational exposure levels (OEL) become increasingly stringent, demanding tailored, top-tier containment solutions to ensure operator safety.

Pharmaceutical Particle Engineering & Formulation Technologies

Milling

Milling, as a critical process in pharmaceutical manufacturing, involves the mechanical reduction of particle sizes of raw materials to create a uniform blend of ingredients essential for consistent drug quality. This reduction is particularly significant in ensuring that the active pharmaceutical ingredients (APIs) and excipients are evenly distributed within a drug formulation, facilitating effective drug delivery and absorption. Among the various milling techniques employed, pin mills and hammer mills are specifically utilized for the coarse milling of particles. These techniques are particularly suited for the initial size reduction of large particles, typically greater than 1 millimeter in diameter. The objective is to break down these particles into a finer powder, generally aiming for particle sizes below 100 microns.