Singleron Biotechnologies GmbH products

The Singleron PythoN Automated Tissue Dissociation System integrates mechanical and enzymatic dissociation. The streamlined workflow quickly dissociates the tissue into high-quality single-cells suspension. Equipped with broad-spectrum sCelLiVE Tissue Dissociation Solution and disposable PythoN Dissociation Tubes, the system can automatically process tissues to obtain highly viable and high-quality single-cell suspensions. The precise digital controling module enables a quick exploration of the best dissociation conditions for a specific tissue type.

Single-cell RNA technologies have rarely been adapted to microorganisms because of challenges related to their size, lower RNA content within a single cell and strict lysis requirements. Singleron developed the first commercially available product to enable high throughput single-cell RNA-Seq from yeast models. This novel technology enables researchers, pathologists, food industries and fermentation businesses to study stochastical variations of gene expression in yeast population through single-cell sequencing with reliable and standardized results. 

DynaSCOPE Single Cell RNA Dynamics Library Kit is the one-and-only commercial kit available that measures the rate and level of nascent RNA over a period of time in single cells.

Single cell RNA sequencing usually requires as an input a single cell suspension prepared from fresh samples. For single cell sequencing of frozen tissues, we offer a specialized product, the GEXSCOPE^® Single Nucleus RNA Library Kit. The GEXSCOPE Single Nucleus RNA Library Kit is a complete solution for transforming tissues into single nuclei and converting the mRNA contained in the single nuclei into NGS libraries. 

Singleron`s sCircle technology enables full length V(D)J region sequencing at single cell level with short-read sequencing.