4 services found
Solvias AG Services
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Polymorphism, Salts & Crystallization
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Solid-State Development Service
The majority of drugs are administered as solids. This means that apart from the molecular structure of the active ingredient, solid-state properties significantly influence the performance of the final product. New substances with pharmaceutical activity are often weak acids or bases or may have unsuitable solid-state properties. In such cases, it may be preferable to develop the drug as a salt or co-crystal ...
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Crystallization Screening Services
Most drug substances are marketed as crystalline material. Having a crystalline drug candidate is beneficial to development processes and simplifies registration. We offer crystallization screening services and also complete crystallization development ...
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Crystallization Development - From Screening to Kilogram Supply
Solvias offers a seamless approach to design and optimize a robust and scalable crystallization process together with kilogram supply of API under GMP, if ...
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Single Parameters and Specialties
Preformulation Package: Preformulation includes the compiling of solubility profiles (pH dependent and other systems of interest), permeability (logP/D, CaCo2 or other cell-based assays), BCS classification, accelerated chemical stability, basic physico-chemical parameters like pKa, melting point, hygroscopicity, salt screening, and polymorphism ...