1 products found
Taconic Biosciences, Inc. Products
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GEMs - Emerging Animal Models for Research
The Taconic Emerging Models Program offers access to developing models sponsored by various Principal Investigators. Animal models enrolled in the Taconic Emerging Models Program are listed below by sponsor, gene of interest, and Taconic model number. Some Emerging Models require execution of Material Transfer Agreements (MTAs) before orders may be placed. Please check the individual model pages for specific information.
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Taconic - Model Lck-cre - Random Transgenic Model
In order to selectively inactivate genes in a tissue specific manner many laboratories have developed Cre transgenic mouse strains in which the Cre recombinase is expressed under the control of a tissue specific promoter. The Lck-Cre transgenic mouse uses the proximal promoter of the Lck (lymphocyte protein tyrosine kinase) gene, which is first expressed early in thymocyte development at the double negative stage. After T cells fully mature, the level of ...