V-Wave Ltd.
V-WAVE was established in Israel in 2009 with a focus on developing percutaneous implantable technologies for patients with chronic heart failure. Technology designed by V-Wave, highlighted by its Ventura Interatrial Shunt System, was designed to help heart failure patients with relief of symptoms, reduced hospitalizations, and improved quality of life. V-Wave is a privately held company with offices in Caesarea, Israel and Agoura Hills, California.
Company details
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- Business Type:
- Technology
- Industry Type:
- Clinical Services
- Market Focus:
- Globally (various continents)
About Us
Advancing the Flow of Life
At V-WAVE, we are driven to deliver breakthrough ideas and technology to the healthcare world with a focus on cardiovascular disease. V-Wave is built on a foundation of science, engineering, and medicine, and is dedicated to achieving our vision to help patients around the world.
V-Wave will support everyone in this mission: from patients, families and loved ones who live this struggle every single day, to doctors, nurses, and other healthcare professionals who have dedicated their careers to this challenge.
Our mission is to give hope and restore quality to life for those who need it most.
Our History
V-Wave was established in 2009 in Israel to develop interatrial shunt devices for patients suffering from chronic heart failure. The goal is to use the shunt to lower left atrial pressure (LAP) and thereby reduce symptoms and improve clinical outcomes. The initial concept focused on a device implanted with a minimally invasive catheter-based procedure that incorporated a novel hourglass design with venturi-like flow efficiency and a one-way tissue valve. The V-Wave shunt was first implanted in a heart failure patient in October 2013.
In 2015, well-known interventional cardiologists and serial medtech entrepreneurs, Neal Eigler, MD and Frank Litvack, MD, joined V-Wave as CEO and Board Chairperson, respectively.
In 2016 V-Wave shared results of its early experience in a multi-center study showing a very high rate of device implantation success, excellent safety, and relief of symptoms. The study gave insights for design improvements, including removal of the valve to achieve the most reliable and long lasting results.
In 2018, the company received regulatory approvals to perform a pivotal randomized, double-blinded, controlled clinical trial – RELIEVE-HF – to assess the safety and effectiveness of the V-Wave Ventura® Interatrial Shunt System in heart failure patients that remain symptomatic despite standard of care treatment. The study is ongoing with a target enrollment of 500 to 700 patients.
In 2020, V-Wave received CE Mark for the Ventura Interatrial Shunt System, allowing for eventual commercial use in Europe.
V-Wave is a privately held company, headquartered in Israel with offices in Southern California.