Vala Sciences products

Background: Microglia are central nervous system innate immune support cells that function remarkably like peripheral macrophages [1]. Microglia continually monitor neuronal function through direct cell-cell contacts and exert neuroprotective effects in response to stress [2]. By maintaining brain homeostasis, clearing cellular debris [3], pruning synapses [4], and eliminating protein aggregates [5], microglia play key roles in neurodevelopment [6], Alzheimer’s Disease [7], Parkinson’s Disease [8], ALS [9], traumatic brain injury [10], and many other central nervous system conditions

Lipid droplets are the primary fat storage organelles of fat cells (adipocytes). Lipid droplet size, and number are altered by anti-diabetic and anti-obesity drugs and these effects can be quantified utilizing Vala Science Inc’s Lipid Droplet Kit. The kit can be utilized to quantify lipid droplets in human primary adipocytes, murine 3T3L1 adipocytes, as well as primary or immortalized hepatocytes.

Vala’s Structured Illumination Microscopy (SIM™) matches the resolution of best-in-class confocal microscopes at the fast speed of lower-resolution drug screening tools.  SIM offers the smallest footprint, with the best ease-of-use, and at half the price of competing tools.