Arthus Biosystems - Model IK00201 - S-Adenosyl-L-Methionine (SAM) ELISA Kit Datasheet

Methionine is an amino acid with sulfur methyl group, which is converted into S-adenosyl methionine (SAM) with ATP by methionine adenosyltransferase (EC 2.5.1 6). SAM is the sole methyl group donor to* over 50 kinds of biologically active substances such as DNA, RNA. protein, phospholipids, hormones and neurotransmitters, etc. After methyl group Is transferred away from SAM under a mehtyltransferase. S-adenosylhomocysteme is formed. which Is further metabolized into homocysteine |Hcy) after adenosine is removed The homocysteine is metabolized to methionine through N5-methyl tetrahydrofolate methyltransferase (EC1.1.1.68) and coenzyme vitamin B12 catalytic pathway accepting methyl from N5-methyHetrahydrofoiate. This is methionine cycle.