Astrea Bioseparations Ltd.

EtoxiClear Adsorbent - Brochure

Endotoxin are lipopolysaccharides (LPS) derived from the cell membrane of Gram-negative
bacteria and are often found as impurities in final pharmaceutical products. Endotoxin elicit a
variety of pathophysiological effects and according to the pharmacopoeia the maximum permitted
level of endotoxin for intravenous products is 5 EU (endotoxin units) per kg adult per hour.

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