antigen-specificity Downloads
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Hepatitis B core recombinant antigen isolated from E. coli and purified by chromatographic methodologies. Description: Hepatitis B core antigen (HBcAg) is the major component of the core particles of Hepatitis B Virus (HBV). Particles have a size of 27 nm and contain a circular double-stranded DNA molecule, a specific DNA-polymerase and HBcAg. ...
ProT2® MHC Class II Tetramers track antigen-specific CD4+ T cells with the most comprehensive class II tetramer catalog range now also available for H-2 IAb, IAd, IAg7. ...
The M2 antibodies belong to the group of Anti-Mitochondrial Antibodies (AMA) and are strongly associated with PBC. At least 9 distinct AMA have been identified, which have been classified M1-M9 according to their antigen specificity and disease association. Of these, only the M2 subtype approaches absolute specificity for PBC. Indeed, about 95 % of PBC patients have M2 autoantibodies and, ...
Recently, ex vivo enrichment protocols based on the use of MHC class I tetramers that allows the detection and characterization of rare antigen-specific CD8+ T-cell populations as well as an estimation of their frequency has been reported. Vaccine development would be largely influenced by this ...
The serological diagnosis of infectious diseases characterized by persistent fever is based on the agglutination reaction which undergoes between the antigen and specific antibodies which may be present in the patient’s ...
![GeneTex - Model CD19 -[HIB19] (PE-Cy7) - Antibody PARENT - Brochure](/_amplify/image?url=https:%2F%2Fd32zuqhgcrpxli.cloudfront.net%2FeyJidWNrZXQiOiJlZS1maWxlcyIsImtleSI6ImZpbGVzLzExMzU1Ny9kb3dubG9hZC8xMDAzMDczLzExMzU1N18xOV8yMDIwMTAyOTA1NTQzNDUyNTA1ODdfdGh1bWJuYWlsX2JpZy5qcGciLCJlZGl0cyI6eyJyZXNpemUiOnsiZml0IjoiY29udGFpbiIsImJhY2tncm91bmQiOnsiciI6MjU1LCJnIjoyNTUsImIiOjI1NSwiYWxwaGEiOjF9LCJ3aWR0aCI6MjQwLCJoZWlnaHQiOjE0NX19fQ==&w=250&h=145&format=webp&q=60 "GeneTex - Model CD19 -[HIB19] (PE-Cy7) - Antibody PARENT - Brochure")
The HIB19 antibody reacts with human CD19, a 95 kDa glycoprotein which acts as a co-receptor, along with CD21, CD81 and CD225, in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary ...
It is estimated that there are approximately 1010–1011 B cells in a human adult. A BCR is composed of two identical heavy chains generated by recombination of V, D and J segments and two identical light chains generated by recombination of V and J segments. Human BCRs undergo recombination at these variable regions, generating a large diverse receptor profile for each cell. Utilizing ...
PLUVICTO is a radioligand therapeutic agent indicated for the treatment of adult patients with prostate-specific membrane antigen (PSMA)-positive metastatic castration-resistant prostate cancer (mCRPC) who have been treated with androgen receptor (AR) pathway inhibition and taxane-based ...
T cells play critical effector and regulatory roles in adaptive immune responses to bacteria. And MHC Tetramers have been proved to be very effective in identifying antigen-specific T cells by flow cytometry, even those present at low frequencies in fresh populations of lymphocytes sampled directly ex ...
Western blot analysis on different cell lysates using anti-LMNB2 rabbit polyclonal antibodies. Polyclonal antibodies (PAbs) are a mixture of antibodies that are secreted by different B cell lineages. These antibodies are actually a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope on an antigen. ...
ByHuabio
AdvanBlock™-Fluor is a novel blocking solution, optimized to enhance specific antibody-antigen interactions for fluorescent Western Blots. This all-in-one blocking solution is designed to improve sensitivity and decrease overall background. Non-specific binding caused by low quality antibodies is reduced while signal from the specific antibody-antigen complex is stabilized and enhanced. ...
ELISPOT assays are a key research tool for enumerating antigen-specific T and B cells in PBMC. As both T and B cells occur in major classes, immune monitoring has to be concerned with identifying these as well. So far, ELISPOT assays have been primarily done single or double color. We report the development of four color T and B cell ELISPOT assays. Cells secreting any of the four analytes can ...
Prostate cancer is one of the leading causes of morbidity and mortality in men in the western world, and the second most common cancer in men worldwide. Imaging of the prostate-specific membrane antigen (PSMA) has become an essential tool for managing patients with recurrent prostate cancer and 68Ga PSMA-11 is one of the most frequently employed radiopharmaceuticals. ...
CanCer MarkersAlpha FetoproteinCarcinogenic Embryonic AntigenProstate Specific Antigen, TotalProstate Specific Antigen, FreeCA 125CA 19-9CA 15-3CardiaCCK-MBTroponin ITroponin TPro-BNP/BNPUltaSenstitive CRPMyoglobin allergyIgEThyroidThyroxine, Total (Total T4)Thyroxine, Free (Free T4)Triiodothyronine, Total (Total ...
ProM2® MHC Class II Monomers, biotinylated enabling specialist assays for defined MHC Class II peptide target interactions. Best in class MHC Class II Monomers: ProM2® Class II MHC Monomers are pre-biotinylated and can be readily adapted either to detect and separate single-antigen specific T cells or implement specialist solid or solution phase immunoassays for measuring interactions of ...
LOCAMETZ, after radiolabeling with gallium-68, is a radioactive diagnostic agent indicated for positron emission tomography (PET) of prostate-specific membrane antigen (PSMA)-positive lesions in men with prostate cancer: with suspected metastasis who are candidates for initial definitive therapy, with suspected recurrence based on elevated serum prostate-specific antigen (PSA) level. for ...
Rapid chromatographic immunoassay for the qualitative detection of specific antigens to SARS-CoV-2 present in human nasopharynx. Result in: 15-30 minutes. Simple procedure. Specimen: nasopharyngeal swab. Sensitivity and specificity: As recommended by WHO. Test kits contains all needed materials. ...
Targeted at key clinical decision points.Mimics performance of patient sample.Unsurpassed performance and stability.Commutability across all platforms.Tri - level control 3 x 4 x 5ml kit size.30 month closed vial stability at -20C.10 day open vial stability at 2- 8C.Dropper system for convenient, optimised usage.MULTICHEM IA pLUs: immunoassay analyTe lisTCanCer Markersalpha ...
Enzyme immunoassay for the detection of specific RA antibodies (anti-CCP2) of IgG class in human serum or plasma. Microtitre wells are coated with the citrulinated synthetic peptides of 2. generation as an antigen. If specific antibodies are present, they bind to the antigen, are labeled by the Conjugate in the following steps and are detected by color reaction with a single component substrate ...
Enzyme immunoassay for the determination of IgG antibodies to dsDNA antigen in human serum or plasma. Microtitre wells are coated with highly purified native antigen dsDNA. If specific antibodies are present, they bind to the antigen, are labeled by the Conjugate in the following steps and are detected by color reaction with a single component substrate (TMB-Complete). The kit allows 96 tests, ...